Performance of the walking trail making test in older adults with white matter hyperintensities.
Cognitive dysfunction
Gait analysis
Motor deficits
Small vessel disease
Trail making test
White matter hyperintensities
Journal
World journal of psychiatry
ISSN: 2220-3206
Titre abrégé: World J Psychiatry
Pays: United States
ID NLM: 101610480
Informations de publication
Date de publication:
19 Jan 2024
19 Jan 2024
Historique:
received:
26
08
2023
revised:
30
10
2023
accepted:
21
12
2023
medline:
8
2
2024
pubmed:
8
2
2024
entrez:
8
2
2024
Statut:
epublish
Résumé
Several studies have reported that the walking trail making test (WTMT) completion time is significantly higher in patients with developmental coordination disorders and mild cognitive impairments. We hypothesized that WTMT performance would be altered in older adults with white matter hyperintensities (WMH). To explore the performance in the WTMT in older people with WMH. In this single-center, observational study, 25 elderly WMH patients admitted to our hospital from June 2019 to June 2020 served as the WMH group and 20 participants matched for age, gender, and educational level who were undergoing physical examination in our hospital during the same period served as the control group. The participants completed the WTMT-A and WTMT-B to obtain their gait parameters, including WTMT-A completion time, WTMT-B completion time, speed, step length, cadence, and stance phase percent. White matter lesions were scored according to the Fazekas scale. Multiple neuropsychological assessments were carried out to assess cognitive function. The relationships between WTMT performance and cognition and motion in elderly patients with WMH were analyzed by partial Pearson correlation analysis. Patients with WMH performed significantly worse on the choice reaction test (CRT) (0.51 ± 0.09 s Older adults with WMH showed obviously poorer WTMT performance. WTMT could be a potential indicator for cognitive and motor deficits in patients with WMH.
Sections du résumé
BACKGROUND
BACKGROUND
Several studies have reported that the walking trail making test (WTMT) completion time is significantly higher in patients with developmental coordination disorders and mild cognitive impairments. We hypothesized that WTMT performance would be altered in older adults with white matter hyperintensities (WMH).
AIM
OBJECTIVE
To explore the performance in the WTMT in older people with WMH.
METHODS
METHODS
In this single-center, observational study, 25 elderly WMH patients admitted to our hospital from June 2019 to June 2020 served as the WMH group and 20 participants matched for age, gender, and educational level who were undergoing physical examination in our hospital during the same period served as the control group. The participants completed the WTMT-A and WTMT-B to obtain their gait parameters, including WTMT-A completion time, WTMT-B completion time, speed, step length, cadence, and stance phase percent. White matter lesions were scored according to the Fazekas scale. Multiple neuropsychological assessments were carried out to assess cognitive function. The relationships between WTMT performance and cognition and motion in elderly patients with WMH were analyzed by partial Pearson correlation analysis.
RESULTS
RESULTS
Patients with WMH performed significantly worse on the choice reaction test (CRT) (0.51 ± 0.09 s
CONCLUSION
CONCLUSIONS
Older adults with WMH showed obviously poorer WTMT performance. WTMT could be a potential indicator for cognitive and motor deficits in patients with WMH.
Identifiants
pubmed: 38327891
doi: 10.5498/wjp.v14.i1.102
pmc: PMC10845218
doi:
Types de publication
Journal Article
Langues
eng
Pagination
102-110Informations de copyright
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflict-of-interest statement: The authors report no conflict of interest.