Lupus-Induced Accelerated Heart Failure in a Young African American Female: Cardiovascular and Systemic Complications of Noncompliance to Maintenance Therapy and the Social Determinants of Cardiovascular Disease.

cardiomyopathy heart failure hydroxychloroquine left ventricular hypertrophy (lvh) social determinants of health (sdoh) systemic lupus erythema

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
Jan 2024
Historique:
accepted: 07 01 2024
medline: 8 2 2024
pubmed: 8 2 2024
entrez: 8 2 2024
Statut: epublish

Résumé

Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disorder characterized by dysregulations of the immune system with intermittent and remitting symptoms. SLE affects multiple organs and systems, including the cardiovascular system. This condition is associated with an increased risk of cardiovascular disease, particularly in younger patients. Our case report describes a patient who rapidly developed structural, functional, and electrophysiological cardiac abnormalities due to lupus-induced cardiomyopathy. The accelerating cardiac events were the result of medication noncompliance. Myocarditis and other potentially fatal cardiac complications associated with SLE have been the subject of numerous studies. This presentation appears to be the first to emphasize the rarity of lupus-induced cardiomyopathy, the importance of treatment adherence, the adverse cardiac effects of targeted therapeutic interventions, and the influence of social determinants of cardiovascular health on a patient's prognosis.

Identifiants

pubmed: 38327922
doi: 10.7759/cureus.51819
pmc: PMC10847065
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e51819

Informations de copyright

Copyright © 2024, Okorie et al.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Auteurs

Ikpechukwu J Okorie (IJ)

Internal Medicine, Richmond University Medical Center, New York, USA.

Edmund Appiah-Kubi (E)

Internal Medicine, Allegheny Health Network, Pittsburgh, USA.

Philipa Owusu-Antwi (P)

Psychiatry, Richmond University Medical Center, New York, USA.

Evans Takyi (E)

Internal Medicine, American University of Antigua, New York, USA.

Derek Ugwendum (D)

Internal Medicine, Richmond University Medical Center, New York, USA.

Annmarie Fernando (A)

Internal Medicine, Richmond University Medical Center, New York, USA.

Muhammed Atere (M)

Medicine, Richmond University Medical Center, New York, USA.

Jay Nfonoyim (J)

Pulmonary and Critical Care, Richmond University Medical Center, New York, USA.

Classifications MeSH