Self-control is associated with health-relevant disparities in buccal DNA-methylation measures of biological aging in older adults.
Biological aging
DNA-methylation
Health
Life span
Pace of aging
Self-control
Journal
Clinical epigenetics
ISSN: 1868-7083
Titre abrégé: Clin Epigenetics
Pays: Germany
ID NLM: 101516977
Informations de publication
Date de publication:
08 Feb 2024
08 Feb 2024
Historique:
received:
08
09
2023
accepted:
29
01
2024
medline:
9
2
2024
pubmed:
9
2
2024
entrez:
8
2
2024
Statut:
epublish
Résumé
Self-control is a personality dimension that is associated with better physical health and a longer lifespan. Here, we examined (1) whether self-control is associated with buccal and saliva DNA-methylation (DNAm) measures of biological aging quantified in children, adolescents, and adults, and (2) whether biological aging measured in buccal DNAm is associated with self-reported health. Following preregistered analyses, we computed two DNAm measures of advanced biological age (principal-component PhenoAge and GrimAge Acceleration) and a DNAm measure of pace of aging (DunedinPACE) in buccal samples from the German Socioeconomic Panel Study (SOEP-G[ene], n = 1058, age range 0-72, M
Identifiants
pubmed: 38331797
doi: 10.1186/s13148-024-01637-7
pii: 10.1186/s13148-024-01637-7
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
22Subventions
Organisme : NIH HHS
ID : P2CHD042849
Pays : United States
Informations de copyright
© 2024. The Author(s).
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