Implementation of a lifestyle and life-skills intervention to prevent weight-gain and cardiometabolic abnormalities in young people with first-episode psychosis as part of routine care: The Keeping the Body in Mind program.

antipsychotic agents body weights and measures diet, food, and nutrition exercise life style mental disorders schizophrenia spectrum and other psychotic disorders

Journal

Early intervention in psychiatry
ISSN: 1751-7893
Titre abrégé: Early Interv Psychiatry
Pays: Australia
ID NLM: 101320027

Informations de publication

Date de publication:
09 Feb 2024
Historique:
revised: 28 11 2023
received: 21 08 2023
accepted: 24 01 2024
medline: 9 2 2024
pubmed: 9 2 2024
entrez: 9 2 2024
Statut: aheadofprint

Résumé

In 2013, a cluster-controlled pilot study found the 12-week Keeping the Body in Mind (KBIM) lifestyle and life skills intervention was able to prevent weight gain in a small sample of youth experiencing first-episode psychosis (FEP) with fewer than 4 weeks of antipsychotic exposure. This study aims to evaluate the effectiveness of KBIM as routine care on anthropometry and metabolic biochemistry in a larger sample of youth with FEP across three community mental health services. This retrospective chart audit was conducted on youth with FEP, prescribed a therapeutic dose of antipsychotic medication, and who engaged with KBIM between 2015 and 2019. Primary outcomes were weight and waist circumference. Secondary outcomes were blood pressure, blood glucose, and blood lipids. Outcomes were collected in at baseline and at 12 weeks. Data on program engagement were obtained from the participant's medical file. One-hundred and eighty-two people met inclusion criteria, and up to 134 people had baseline and 12-week data on one or more outcome. Mean number of sessions attended was 11.1 (SD = 7.3). Increases in weight and waist circumference were limited to 1.5 kg (SD = 5.3, t(133) = 3.2, p = .002) and 0.7 cm (SD = 5.8, t(109) = 1.2, p = .23) respectively. Eighty-one percent of participants did not experience clinically significant weight gain (>7% of baseline weight). There were no significant changes in blood pressure or metabolic biochemistry. The prevention of substantial gains in weight and waist circumference observed in the initial pilot study was maintained with implementation of KBIM as part of routine clinical care for youth with FEP.

Identifiants

pubmed: 38334187
doi: 10.1111/eip.13508
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 The Authors. Early Intervention in Psychiatry published by John Wiley & Sons Australia, Ltd.

Références

Alberti, K. G. M. M., Zimmet, P., & Shaw, J. (2006). Metabolic syndrome-A new world-wide definition. A consensus statement from the international diabetes federation. Diabetic Medicine, 23(5), 469-480. https://doi.org/10.1111/j.1464-5491.2006.01858.x
Alvarez-Jimenez, M., Gonzalez-Blanch, C., Crespo-Facorro, B., Hetrick, S., Rodriguez-Sanchez, J. M., Perez-Iglesias, R., & Luis, J. (2008). Antipsychotic-induced weight gain in chronic and first-episode psychotic disorders. CNS Drugs, 22(7), 547-562. https://doi.org/10.2165/00023210-200822070-00002
Alvarez-Jiménez, M., Hetrick, S. E., González-Blanch, C., Gleeson, J. F., & McGorry, P. D. (2008). Non-pharmacological management of antipsychotic-induced weight gain: Systematic review and meta-analysis of randomised controlled trials. British Journal of Psychiatry, 193(2), 101-107. https://doi.org/10.1192/bjp.bp.107.042853
Arango, C., Giráldez, M., Merchán-Naranjo, J., Baeza, I., Castro-Fornieles, J., Alda, J.-A., Martinez-Cantarero, C., Moreno, C., de Andrés, P., & Cuerda, C. (2014). Second-generation antipsychotic use in children and adolescents: A six-month prospective cohort study in drug-naïve patients. Journal of the American Academy of Child & Adolescent Psychiatry, 53(11), 1179-1190. https://doi.org/10.1016/j.jaac.2014.08.009
Baeza, I., Vigo, L., de la Serna, E. et al. (2017). The effects of antipsychotics on weight gain, weight-related hormones and homocysteine in children and adolescents: a 1-year follow-up study. Eur Child Adolesc Psychiatry, 26, 35-46. https://doi.org/10.1007/s00787-016-0866-x
Correll, C. U., Manu, P., Olshanskiy, V., Napolitano, B., Kane, J. M., & Malhotra, A. K. (2009). Cardiometabolic risk of second-generation antipsychotic medications during first-time use in children and adolescents. JAMA, 302(16), 1765-1773. https://doi.org/10.1001/jama.2009.1549
Correll, C. U., Sikich, L., Reeves, G., & Riddle, M. (2013). Metformin for antipsychotic-related weight gain and metabolic abnormalities: When, for whom, and for how long? American Journal of Psychiatry, 170(9), 947-952. https://doi.org/10.1176/appi.ajp.2013.13060771
Correll, C. U., Solmi, M., Veronese, N., Bortolato, B., Rosson, S., Santonastaso, P., Thapa-Chhetri, N., Fornaro, M., Gallicchio, D., & Collantoni, E. (2017). Prevalence, incidence and mortality from cardiovascular disease in patients with pooled and specific severe mental illness: A large-scale meta-analysis of 3,211,768 patients and 113,383,368 controls. World Psychiatry, 16(2), 163-180. https://doi.org/10.1002/wps.20420
Curtis, J., Newall, H. D., & Samaras, K. (2012). The heart of the matter: Cardiometabolic care in youth with psychosis. Early Intervention in Psychiatry, 6(3), 347-353. https://doi.org/10.1111/j.1751-7893.2011.00315.x
Curtis, J., Watkins, A., Rosenbaum, S., Teasdale, S., Kalucy, M., Samaras, K., & Ward, P. B. (2016). Evaluating an individualized lifestyle and life skills intervention to prevent antipsychotic-induced weight gain in first-episode psychosis. Early Intervention in Psychiatry, 10(3), 267-276. https://doi.org/10.1111/eip.12230
Curtis, J., Watkins, A., Teasdale, S., Lederman, O., Kalucy, M., Lappin, J., Samaras, K., Rosenbaum, S., & Ward, P. B. (2018). 2-year follow-up: Still keeping the body in mind. Australian & New Zealand Journal of Psychiatry, 52(6), 602-603. https://doi.org/10.1177/0004867417753553
Firth, J., Siddiqi, N., Koyanagi, A., Siskind, D., Rosenbaum, S., Galletly, C., Allan, S., Caneo, C., Carney, R., Carvalho, A., Chatterton, M., Correll, C. U., Curtis, J., Gaughran, F., Heald, A., Hoare, E., Jackson, S., Kisely, S., Lovell, K., & Maj, M. (2019). The lancet psychiatry commission: A blueprint for protecting physical health in people with mental illness. Lancet Psychiatry, 6(8), 675-712. https://doi.org/10.1016/S2215-0366(19)30132-4
Galletly, C., Castle, D., Dark, F., Humberstone, V., Jablensky, A., Killackey, E., Kulkarni, J., McGorry, P., Nielssen, O., & Tran, N. (2016). Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the management of schizophrenia and related disorders. Australian & New Zealand Journal of Psychiatry, 50(5), 410-472. https://doi.org/10.1177/0004867416641195
Hjorthøj, C., Stürup, A. E., McGrath, J. J., & Nordentoft, M. (2017). Years of potential life lost and life expectancy in schizophrenia: A systematic review and meta-analysis. The Lancet Psychiatry, 4(4), 295-301. https://doi.org/10.1016/S2215-0366(17)30078-0
Naslund, J. A., Whiteman, K. L., McHugo, G. J., Aschbrenner, K. A., Marsch, L. A., & Bartels, S. J. (2017). Lifestyle interventions for weight loss among overweight and obese adults with serious mental illness: A systematic review and meta-analysis. General Hospital Psychiatry, 47, 83-102. https://doi.org/10.1016/j.genhosppsych.2017.04.003
Newall, H., Myles, N., Ward, P. B., Samaras, K., Shiers, D., & Curtis, J. (2012). Efficacy of metformin for prevention of weight gain in psychiatric populations: A review. International Clinical Psychopharmacology, 27(2), 69-75. https://doi.org/10.1097/YIC.0b013e32834d0a5b
Norton, K. N. L. (2011). Pre-exercise screening: Guide to the Australian adult pre-exercise screening system. Retrieved 07 November 2023, from http://bp-fitnessaustralia-production.s3.amazonaws.com/uploads/uploaded_file/file/195/Australian-Adult-Pre-Exercise-Screening-Textbook.pdf
Perry, B. I., Osimo, E. F., Upthegrove, R., Mallikarjun, P. K., Yorke, J., Stochl, J., Perez, J., Zammit, S., Howes, O., & Jones, P. B. (2021). Development and external validation of the psychosis metabolic risk calculator (PsyMetRiC): A cardiometabolic risk prediction algorithm for young people with psychosis. The Lancet Psychiatry, 8(7), 589-598. https://doi.org/10.1016/S2215-0366(21)00114-0
Ratamess, N. A., Alvar, B. A., Evetoch, T. E., Housh, T. J., Ben Kibler, W., Kraemer, W. J., & Triplett, N. T. (2009). Progression models in resistance training for healthy adults. Medicine and Science in Sports and Exercise, 41(3), 687-708. https://doi.org/10.1249/MSS.0b013e3181915670
Shiers, D., & Curtis, J. (2014). Cardiometabolic health in young people with psychosis. The Lancet Psychiatry, 1(7), 492-494. https://doi.org/10.1016/S2215-0366(14)00072-8
Strassnig, M., Kotov, R., Cornaccio, D., Fochtmann, L., Harvey, P. D., & Bromet, E. J. (2017). Twenty-year progression of body mass index in a county-wide cohort of people with schizophrenia and bipolar disorder identified at their first episode of psychosis. Bipolar Disorders, 19(5), 336-343. https://doi.org/10.1111/bdi.12505
Vandenberghe, F., Gholam-Rezaee, M., Saigí-Morgui, N., Delacrétaz, A., Choong, E., Solida-Tozzi, A., Kolly, S., Thonney, J., Gallo, S. F., Hedjal, A., Ambresin, A. E., von Gunten, A., Conus, P., & Eap, C. B. (2015). Importance of early weight changes to predict long-term weight gain during psychotropic drug treatment. Journal of Clinical Psychiatry, 76(11), e1417-e1423. https://doi.org/10.4088/JCP.14m09358
World Health Organization (WHO). (1995). Physical status: The use of and interpretation of anthropometry, report of a WHO expert committee. WHO Retrieved from https://apps.who.int/iris/handle/10665/37003
World Health Organization (WHO). (2010). Global recommendations on physical activity for health. WHO Retrieved from https://who.int/publications/i/item/9789241599979

Auteurs

Jackie Curtis (J)

Discipline of Psychiatry and Mental Health, School of Clinical Medicine, UNSW Sydney, Kensington, New South Wales, Australia.
Mindgardens Neuroscience Network, Sydney, New South Wales, Australia.
Keeping the Body in Mind Program, South Eastern Sydney Local Health District, Bondi Junction, New South Wales, Australia.

Scott B Teasdale (SB)

Discipline of Psychiatry and Mental Health, School of Clinical Medicine, UNSW Sydney, Kensington, New South Wales, Australia.
Mindgardens Neuroscience Network, Sydney, New South Wales, Australia.

Rachel Morell (R)

Discipline of Psychiatry and Mental Health, School of Clinical Medicine, UNSW Sydney, Kensington, New South Wales, Australia.
Mindgardens Neuroscience Network, Sydney, New South Wales, Australia.

Prarthna Wadhwa (P)

Keeping the Body in Mind Program, South Eastern Sydney Local Health District, Bondi Junction, New South Wales, Australia.

Andrew Watkins (A)

Mindgardens Neuroscience Network, Sydney, New South Wales, Australia.
Faculty of Health, University of Technology, Sydney, New South Wales, Australia.

Oscar Lederman (O)

Keeping the Body in Mind Program, South Eastern Sydney Local Health District, Bondi Junction, New South Wales, Australia.
School of Health Sciences, UNSW Sydney, Kensington, New South Wales, Australia.

Catherine O'Donnell (C)

Mindgardens Neuroscience Network, Sydney, New South Wales, Australia.

Hamish Fibbins (H)

Mindgardens Neuroscience Network, Sydney, New South Wales, Australia.
Keeping the Body in Mind Program, South Eastern Sydney Local Health District, Bondi Junction, New South Wales, Australia.

Philip B Ward (PB)

Discipline of Psychiatry and Mental Health, School of Clinical Medicine, UNSW Sydney, Kensington, New South Wales, Australia.
Schizophrenia Research Unit, South Western Sydney Local Health District and Ingham Institute of Applied Medical Research, Liverpool, New South Wales, Australia.

Classifications MeSH