Hierarchical porous PLLA/ACP fibrous membrane towards bone tissue scaffold.
Bone tissue scaffold
Calcium phosphate
Electrospinning
Hierarchical porosity
Poly(L-lactic acid)
Journal
Journal of the mechanical behavior of biomedical materials
ISSN: 1878-0180
Titre abrégé: J Mech Behav Biomed Mater
Pays: Netherlands
ID NLM: 101322406
Informations de publication
Date de publication:
05 Feb 2024
05 Feb 2024
Historique:
received:
11
12
2023
revised:
30
01
2024
accepted:
03
02
2024
medline:
10
2
2024
pubmed:
10
2
2024
entrez:
9
2
2024
Statut:
aheadofprint
Résumé
Electrospun fibres have emerged as vital components in developing tissue engineering scaffolds. Calcium phosphate-based materials, renowned for their bioactivity and biocompatibility, have garnered considerable attention in biomedical applications. This study focuses on the incorporation of amorphous calcium phosphate (ACP) nanoparticles into poly(L-lactic acid) (PLLA) to produce electrospun PLLA/ACP fibrous membranes. Subsequent treatment with acetone yielded a hierarchical porous structure, boasting an ultra-high surface area of 94.7753 ± 0.3884 m
Identifiants
pubmed: 38335647
pii: S1751-6161(24)00087-0
doi: 10.1016/j.jmbbm.2024.106455
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
106455Informations de copyright
Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.