Impact of a pulmonary embolism response team in the prognosis of patients with acute symptomatic pulmonary embolism.

Tromboembolia de pulmón equipo multidisciplinar multidisciplinary team prognosis pronóstico pulmonary embolism

Journal

Revista clinica espanola
ISSN: 2254-8874
Titre abrégé: Rev Clin Esp (Barc)
Pays: Spain
ID NLM: 101632437

Informations de publication

Date de publication:
07 Feb 2024
Historique:
medline: 10 2 2024
pubmed: 10 2 2024
entrez: 9 2 2024
Statut: aheadofprint

Résumé

The effect of a Pulmonary Embolism Response Team (PERT) in the short-term prognosis of patients with acute symptomatic pulmonary embolism (PE) lacks clarity. We therefore aimed at evaluating the effect of a PERT team on short-term mortality among patients with acute PE. We retrospectively reviewed consecutive patients with acute symptomatic PE enrolled in a single-center registry between 2007 and 2022. We used propensity score matching to compare treatment effects for patients with similar predicted probabilities of receiving management by the PERT team. The primary outcome was all-cause mortality within 30 days following the diagnosis of PE. The secondary outcome was 30-day PE-related mortality. Of the 2,902 eligible patients who had acute symptomatic PE, 223 (7.7%; 95% confidence interval [CI], 6.7%-8.7%) were managed by the PERT team. Two hundred and seven patients who were treated by the PERT were matched with 207 patients who were not. Matched pairs did not show a statistically significant lower all-cause (odds ratio [OR], 1.09; 95% CI, 0.63-1.89) or PE-related death (OR, 1.30; 95% CI, 0.47-3.62) for PERT management compared with no PERT management through 30 days after diagnosis of PE. Our results suggest that multidisciplinary care of patients with acute symptomatic PE by a PERT team is not associated with a significant reduction in short-term all-cause or PE-related mortality.

Sections du résumé

BACKGROUND BACKGROUND
The effect of a Pulmonary Embolism Response Team (PERT) in the short-term prognosis of patients with acute symptomatic pulmonary embolism (PE) lacks clarity. We therefore aimed at evaluating the effect of a PERT team on short-term mortality among patients with acute PE.
METHODS METHODS
We retrospectively reviewed consecutive patients with acute symptomatic PE enrolled in a single-center registry between 2007 and 2022. We used propensity score matching to compare treatment effects for patients with similar predicted probabilities of receiving management by the PERT team. The primary outcome was all-cause mortality within 30 days following the diagnosis of PE. The secondary outcome was 30-day PE-related mortality.
RESULTS RESULTS
Of the 2,902 eligible patients who had acute symptomatic PE, 223 (7.7%; 95% confidence interval [CI], 6.7%-8.7%) were managed by the PERT team. Two hundred and seven patients who were treated by the PERT were matched with 207 patients who were not. Matched pairs did not show a statistically significant lower all-cause (odds ratio [OR], 1.09; 95% CI, 0.63-1.89) or PE-related death (OR, 1.30; 95% CI, 0.47-3.62) for PERT management compared with no PERT management through 30 days after diagnosis of PE.
CONCLUSIONS CONCLUSIONS
Our results suggest that multidisciplinary care of patients with acute symptomatic PE by a PERT team is not associated with a significant reduction in short-term all-cause or PE-related mortality.

Identifiants

pubmed: 38336141
pii: S2254-8874(24)00019-5
doi: 10.1016/j.rceng.2024.02.001
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024 Sociedad Española de Medicina Interna (SEMI). Published by Elsevier España, S.L.U. All rights reserved.

Auteurs

Sara González (S)

Servicio de Neumología, Hospital Ramón y Cajal, IRYCIS, Madrid, Spain.

Marta Najarro (M)

Servicio de Urgencias, Hospital Ramón y Cajal, IRYCIS, Madrid, Spain.

Winnifer Briceño (W)

Servicio de Neumología, Hospital Ramón y Cajal, IRYCIS, Madrid, Spain.

Carmen Rodríguez (C)

Servicio de Neumología, Hospital Ramón y Cajal, IRYCIS, Madrid, Spain.

Deisy Barrios (D)

Servicio de Neumología, Hospital Ramón y Cajal, IRYCIS, Madrid, Spain.

Raquel Morillo (R)

Servicio de Neumología, Hospital Ramón y Cajal, IRYCIS, Madrid, Spain; CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain.

Andreína Olavarría (A)

Servicio de Radiología, Hospital Ramón y Cajal, IRYCIS, Madrid, Spain.

Aurora Lietor (A)

Servicio de Medicina Intensiva, Hospital Ramón y Cajal, IRYCIS, Madrid, Spain.

Vicente Gómez Del Olmo (VGD)

Servicio de Medicina Interna, Hospital Ramón y Cajal, IRYCIS, Madrid, Spain.

Álvaro Osorio (Á)

Servicio de Cirugía Vascular, Hospital Ramón y Cajal, IRYCIS, Madrid, Spain.

Ángel Sánchez-Recalde (Á)

Servicio de Cardiología, Hospital Ramón y Cajal, IRYCIS, Madrid, Spain.

Alfonso Muriel (A)

Servicio de Bioestadística, Hospital Ramón y Cajal, IRYCIS, CIBERESP, Madrid, Spain.

David Jiménez (D)

Servicio de Neumología, Hospital Ramón y Cajal, IRYCIS, Madrid, Spain; CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain; Departamento de Medicina, Universidad de Alcalá, Madrid, Spain. Electronic address: djimenez.hrc@gmail.com.

Classifications MeSH