Incidence of Venous Thromboembolism in Pediatric Orthopedics: A Systematic Review.
Deep veinous thrombosis
Musculoskeletal infections
Orthopedics pediatrics
Pulmonary embolisms
Veinous thromboembolism
Journal
Orthopaedics & traumatology, surgery & research : OTSR
ISSN: 1877-0568
Titre abrégé: Orthop Traumatol Surg Res
Pays: France
ID NLM: 101494830
Informations de publication
Date de publication:
07 Feb 2024
07 Feb 2024
Historique:
received:
17
11
2023
revised:
23
01
2024
accepted:
01
02
2024
medline:
10
2
2024
pubmed:
10
2
2024
entrez:
9
2
2024
Statut:
aheadofprint
Résumé
Children undergoing orthopedic procedures often present numerous risk factors for thromboembolism. A recent survey, conducted by the pediatric orthopaedic society of north America (POSNA), indicates that pediatric orthopedic surgeons are unaware of venous thromboembolism (VTE) prevention protocols and feel that certain procedures should require thromboprophylaxis. The aim of this systematic review was to properly assess the incidence of VTE in pediatric orthopedics. By using a thorough and broad search of the literature, the incidence according to different subspecialties of pediatric orthopedics was evaluated. A systematic review on VTE in pediatric orthopedics was conducted. Four databases were searched for articles reporting these events. Three major search concepts: "pediatrics", "orthopedic surgery/trauma" and "VTE complications" were used and broken down in MeSH, EmTree and their free vocabulary synonyms for proper literature review. Two independent authors screened 8467 titles and abstracts. Seventy articles reporting VTE in children treated by orthopedic surgeons were selected for data extraction. We reported median incidences by orthopedic subtypes and by study characteristics with a semi-quantitative review model. The 70 articles yielded a total of 845010 participants. Spine articles (33/70) provided 25,2% of the children included in the review. Trauma studies (16/70) accounted for 47.5% of the participants. The overall VTE median incidence was 0.16% [95%CI 0.0 - 1.01%]. Musculoskeletal infections had a noticeably higher median incidence of 3.5% [CI 0.0 - 13.8%]. Small variations were seen for the other subtypes: trauma, spine and elective surgeries. Subgroups by article characteristics did not differ significantly either. Thrombotic complications are rare events in pediatric orthopedics, but knowledge epidemiologic is important because its potential severity. In this review, VTE median incidence for all orthopedic subtypes was around 0.16% [CI 0.0 - 1.01%]. According to subspecialty assessment, musculoskeletal infections were associated with greater risk of VTE occurrence. III - Systematic review.
Sections du résumé
BACKGROUNDS
BACKGROUND
Children undergoing orthopedic procedures often present numerous risk factors for thromboembolism. A recent survey, conducted by the pediatric orthopaedic society of north America (POSNA), indicates that pediatric orthopedic surgeons are unaware of venous thromboembolism (VTE) prevention protocols and feel that certain procedures should require thromboprophylaxis. The aim of this systematic review was to properly assess the incidence of VTE in pediatric orthopedics. By using a thorough and broad search of the literature, the incidence according to different subspecialties of pediatric orthopedics was evaluated.
METHODS
METHODS
A systematic review on VTE in pediatric orthopedics was conducted. Four databases were searched for articles reporting these events. Three major search concepts: "pediatrics", "orthopedic surgery/trauma" and "VTE complications" were used and broken down in MeSH, EmTree and their free vocabulary synonyms for proper literature review. Two independent authors screened 8467 titles and abstracts. Seventy articles reporting VTE in children treated by orthopedic surgeons were selected for data extraction. We reported median incidences by orthopedic subtypes and by study characteristics with a semi-quantitative review model.
RESULTS
RESULTS
The 70 articles yielded a total of 845010 participants. Spine articles (33/70) provided 25,2% of the children included in the review. Trauma studies (16/70) accounted for 47.5% of the participants. The overall VTE median incidence was 0.16% [95%CI 0.0 - 1.01%]. Musculoskeletal infections had a noticeably higher median incidence of 3.5% [CI 0.0 - 13.8%]. Small variations were seen for the other subtypes: trauma, spine and elective surgeries. Subgroups by article characteristics did not differ significantly either.
CONCLUSION
CONCLUSIONS
Thrombotic complications are rare events in pediatric orthopedics, but knowledge epidemiologic is important because its potential severity. In this review, VTE median incidence for all orthopedic subtypes was around 0.16% [CI 0.0 - 1.01%]. According to subspecialty assessment, musculoskeletal infections were associated with greater risk of VTE occurrence.
LEVEL OF EVIDENCE
METHODS
III - Systematic review.
Identifiants
pubmed: 38336248
pii: S1877-0568(24)00032-X
doi: 10.1016/j.otsr.2024.103830
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
103830Informations de copyright
Copyright © 2024. Published by Elsevier Masson SAS.