Mitochondrial Unfolded Protein Response Gene

CLPP female fertility mitochondrial dysfunction mitochondrial stress response oocyte function

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
03 Feb 2024
Historique:
received: 02 01 2024
revised: 28 01 2024
accepted: 02 02 2024
medline: 10 2 2024
pubmed: 10 2 2024
entrez: 10 2 2024
Statut: epublish

Résumé

Mitochondrial unfolded protein stress response (mtUPR) plays a critical role in regulating cellular and metabolic stress response and helps maintain protein homeostasis. Caseinolytic peptidase P (CLPP) is one of the key regulators of mtUPR and promotes unfolded protein degradation. Previous studies demonstrated that global deletion of

Identifiants

DOI: 10.3390/ijms25031866 PMID: 38339144
pubmed: 38339144
pii: ijms25031866
doi: 10.3390/ijms25031866
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Foundation for Embryonic Competence
ID : GR109707

Auteurs

Yagmur Ergun (Y)

Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, CT 06510, USA.
IVIRMA Global Research Alliance, IVIRMA New Jersey, Marlton, NJ 07920, USA.

Aysegul Gizem Imamoglu (AG)

Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, CT 06510, USA.

Mauro Cozzolino (M)

Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, CT 06510, USA.
IVIRMA Global Research Alliance, IVI Roma, 00169 Rome, Italy.
IVIRMA Global Research Alliance, IVI Foundation, Instituto de Investigación Sanitaria La Fe (IIS La Fe), 46026 Valencia, Spain.
ORCID: 0000-0002-5929-2357

Cem Demirkiran (C)

Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, CT 06510, USA.
ORCID: 0000-0002-7073-2819

Murat Basar (M)

Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, CT 06510, USA.
Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale Fertility Center, Orange, CT 06477, USA.
ORCID: 0000-0001-7766-409X

Akanksha Garg (A)

Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, CT 06510, USA.
Department of Metabolism, Digestion and Reproduction, Imperial College London, London SW7 2BX, UK.

Raziye Melike Yildirim (RM)

Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, CT 06510, USA.
ORCID: 0000-0002-2550-6396

Emre Seli (E)

Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, CT 06510, USA.
Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale Fertility Center, Orange, CT 06477, USA.
IVIRMA Global Research Alliance, IVIRMA New Jersey, Basking Ridge, NJ 07920, USA.

Classifications MeSH