Is CT Radiomics Superior to Morphological Evaluation for pN0 Characterization? A Pilot Study in Colon Cancer.

colon cancer lymph node metastasis lymph node morphology radiomics

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
04 Feb 2024
Historique:
received: 24 11 2023
revised: 02 01 2024
accepted: 01 02 2024
medline: 10 2 2024
pubmed: 10 2 2024
entrez: 10 2 2024
Statut: epublish

Résumé

The aim of this study was to compare CT radiomics and morphological features when assessing benign lymph nodes (LNs) in colon cancer (CC). This retrospective study included 100 CC patients (test cohort) who underwent a preoperative CT examination and were diagnosed as pN0 after surgery. Regional LNs were scored with a morphological Likert scale (NODE-SCORE) and divided into two groups: low likelihood (LLM: 0-2 points) and high likelihood (HLM: 3-7 points) of malignancy. The

Identifiants

DOI: 10.3390/cancers16030660 PMID: 38339411
pubmed: 38339411
pii: cancers16030660
doi: 10.3390/cancers16030660
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Italian Association for Cancer Research
ID : IG 2020-ID 24974

Auteurs

Marta Zerunian (M)

Radiology Unit, Department of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy.
Ph.D. School in Translational Medicine and Oncology, Department of Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome, Via Giorgio Nicola Papanicolau-ang. Via di Grottarossa 1035, 00189 Rome, Italy.
ORCID: 0000-0003-4635-7999

Ilaria Nacci (I)

Radiology Unit, Department of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy.
ORCID: 0000-0002-8659-131X

Damiano Caruso (D)

Radiology Unit, Department of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy.
ORCID: 0000-0001-9285-4764

Michela Polici (M)

Radiology Unit, Department of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy.
Ph.D. School in Translational Medicine and Oncology, Department of Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome, Via Giorgio Nicola Papanicolau-ang. Via di Grottarossa 1035, 00189 Rome, Italy.
ORCID: 0000-0001-7331-6901

Benedetta Masci (B)

Radiology Unit, Department of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy.
ORCID: 0000-0003-0935-6364

Domenico De Santis (D)

Radiology Unit, Department of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy.
ORCID: 0000-0002-1197-456X

Paolo Mercantini (P)

Surgery Unit, Department of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy.

Giulia Arrivi (G)

Oncology Unit, Department of Clinical and Molecular Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy.
ORCID: 0000-0003-0541-415X

Federica Mazzuca (F)

Oncology Unit, Department of Clinical and Molecular Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy.

Pasquale Paolantonio (P)

Department of Radiology, San Giovanni Addolorata Hospital Complex, Via dell'Amba Aradam 8, 00184 Rome, Italy.

Emanuela Pilozzi (E)

Pathology Unit, Department of Clinical and Molecular Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy.
ORCID: 0000-0002-7110-9172

Andrea Vecchione (A)

Pathology Unit, Department of Clinical and Molecular Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy.
ORCID: 0000-0002-5497-6856

Mariarita Tarallo (M)

Department of Surgery "Pietro Valdoni", Sapienza University of Rome, Via Giovanni Maria Lancisi 2, 00161 Rome, Italy.
ORCID: 0000-0003-3783-4749

Enrico Fiori (E)

Department of Surgery "Pietro Valdoni", Sapienza University of Rome, Via Giovanni Maria Lancisi 2, 00161 Rome, Italy.
ORCID: 0000-0002-5171-6127

Elsa Iannicelli (E)

Radiology Unit, Department of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy.

Andrea Laghi (A)

Radiology Unit, Department of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy.
ORCID: 0000-0002-3091-7819

Classifications MeSH