Anorexia of ageing is associated with elevated fasted and lower post-prandial ghrelin, independent of ghrelin O-acyltransferase.

Appetite Gut hormones Hunger Malnutrition Older adults

Journal

Appetite
ISSN: 1095-8304
Titre abrégé: Appetite
Pays: England
ID NLM: 8006808

Informations de publication

Date de publication:
01 May 2024
Historique:
received: 02 12 2023
revised: 05 02 2024
accepted: 07 02 2024
pubmed: 11 2 2024
medline: 11 2 2024
entrez: 10 2 2024
Statut: ppublish

Résumé

The role of ghrelin metabolism in anorexia of ageing is unclear. The aim of this study was to determine acyl-ghrelin, total ghrelin, and ghrelin O-acyltransferase concentrations when fasted and in responses to feeding in older adults exhibiting anorexia of ageing. Twenty-five older adults (OA; 15f, 74 ± 7 years, 24.5 kg·m

Identifiants

pubmed: 38341037
pii: S0195-6663(24)00060-6
doi: 10.1016/j.appet.2024.107259
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

107259

Informations de copyright

Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest This work was supported by a Wellcome Trust Institutional Strategic Support Fund award. The authors declare no conflicts of interest.

Auteurs

Adrian Holliday (A)

School of Biomedical, Nutritional, and Sport Science, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK; Human Nutrition and Exercise Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK. Electronic address: adrian.holliday@ncl.ac.uk.

Jordan Warner (J)

School of Biomedical, Nutritional, and Sport Science, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK.

Carl J Hulston (CJ)

School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK.

Bernard M Corfe (BM)

Human Nutrition and Exercise Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK.

Daniel R Crabtree (DR)

The Rowett Institute, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, UK.

Classifications MeSH