Improving Sediment Toxicity Testing for Very Hydrophobic Chemicals: Part 1-Spiking, Equilibrating, and Exposure Quantification.
Aging
Lumbriculus variegatus
Passive dosing
Passive sampling
Sediment toxicity
Spiking
Journal
Environmental toxicology and chemistry
ISSN: 1552-8618
Titre abrégé: Environ Toxicol Chem
Pays: United States
ID NLM: 8308958
Informations de publication
Date de publication:
12 Feb 2024
12 Feb 2024
Historique:
revised:
04
09
2023
received:
12
07
2023
accepted:
22
12
2023
medline:
12
2
2024
pubmed:
12
2
2024
entrez:
12
2
2024
Statut:
aheadofprint
Résumé
Sediment toxicity tests have applications in ecological risk and chemical safety assessments. Despite the many years of experience in testing and the availability of standard protocols, sediment toxicity testing remains challenging with very hydrophobic organic chemicals (VHOCs; i.e., chemicals with a log octanol/water partition coefficient of more than 6). The challenges primarily relate to the chemicals' low aqueous solubilities and slow kinetics, due to which several experimental artifacts may occur. To investigate the potential artifacts, experiments were performed, focusing on spiking and equilibrating (aging) sediments, as well as exposure quantification with passive sampling. The results demonstrated that generally applied, Organisation for Economic Co-operation and Development-recommended spiking (coating) methods may lead to significant chemical losses and the formation of nondissolved, nonbioavailable VHOCs. Direct spiking appeared to be the most optimal, provided that intensive mixing was applied simultaneously. Passive dosing was tested as a novel way of spiking liquid VHOCs, but the approach proved unsuccessful. Intensive postspiking mixing during sediment equilibration for 1 to 2 weeks was shown to be essential for producing a homogeneous system, minimizing the presence of nondissolved chemical (crystals or nonaqueous phase liquids; NAPLs), and creating a stable toxicological response in subsequent toxicity tests. Finally, exposure quantification of VHOCs in sediments through passive sampling was found to be feasible with different polymers, although prolonged equilibration times may be required, and determining sampler/water partition coefficients can be extremely challenging. The results of additional experiments, focusing on toxicity test exposure duration, concentrations above which NAPLs will occur, and ways to distinguish actual toxicity from false-positive results, are presented in Part 2 of this publication series. Environ Toxicol Chem 2024;00:1-11. © 2024 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : CEFIC-LRI
ID : ECO43-IRAS
Organisme : ExxonMobil Biomedical Sciences, Inc
Informations de copyright
© 2024 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.
Références
Alexander, M. (2000). Aging, bioavailability, and overestimation of risk from environmental pollutants. Environmental Science & Technology, 34, 4259-4265.
Cornelissen, G., Wiberg, K., Broman, D. A. G., Arp, H. P. H., Persson, Y., Sundqvist, K., & Jonsson, P. (2008). Freely dissolved concentrations and sediment-water activity ratios of PCDD/Fs and PCBs in the open Baltic sea. Environmental Science & Technology, 42, 8733-8739.
Di Toro, D. M., Zarba, C. S., Hansen, D. J., Berry, W. J., Swartz, R. C., Cowan, C. E., Pavlou, S. P., Allen, H. E., Thomas, N. A., & Paquin, P. R. (1991). Technical basis for establishing sediment quality criteria for nonionic organic chemicals using equilibrium partitioning. Environmental Toxicology and Chemistry, 10, 1541-1583.
Greenberg, M. S., Chapman, P. M., Allan, I. J., Anderson, K. A., Apitz, S. E., Beegan, C., Bridges, T. S., Brown, S. S., Cargill, 4th, J. G., McCulloch, M. C., Menzie, C. A., Shine, J. P., & Parkerton, T. F. (2014). Passive sampling methods for contaminated sediments: Risk assessment and management. Integrated Environmental Assessment and Management, 10, 224-236.
Hiki, K., Fischer, F. C., Nishimori, T., Watanabe, H., Yamamoto, H., & Endo, S. (2021b). Spatiotemporal distribution of hydrophobic organic contaminants in spiked-sediment toxicity tests: Measuring total and freely dissolved concentrations in porewater and overlying water. Environmental Toxicology and Chemistry, 40, 3148-3158.
Hiki, K., Watanabe, H., & Yamamoto, H. (2021a). Sources of variation in sediment toxicity of hydrophobic organic chemicals: Meta-analysis of 10-14-day spiked-sediment tests with Hyalella azteca and Chironomus dilutus. Integrated Environmental Assessment and Management, 17, 1003-1013.
Jonker, M. T. O. (2022). Polyethylene-water and polydimethylsiloxane-water partition coefficients for polycyclic aromatic hydrocarbons and polychlorinated biphenyls: Influence of polymer source and proposed best available values. Environmental Toxicology and Chemistry, 41, 1370-1380.
Jonker, M. T. O., Burgess, R. M., Ghosh, U., Gschwend, P. M., Hale, S. E., Lohmann, R., Lydy, M. J., Maruya, K. A., Reible, D., & Smedes, F. (2020). Ex situ determination of freely dissolved concentrations of hydrophobic organic chemicals in sediments and soils: Basis for interpreting toxicity and assessing bioavailability, risks and remediation necessity. Nature Protocols, 15, 1800-1828.
Jonker, M. T. O., & Diepens, N. J. (2024). Improving sediment toxicity testing for very hydrophobic chemicals: Part 2-Exposure duration, upper limit test concentrations, and distinguishing actual toxicity from physical effects. Environmental Toxicology and Chemistry, this issue.
Jonker, M. T. O., Van der Heijden, S. A., Kotte, M., & Smedes, F. (2015). Quantifying the effects of temperature and salinity on partitioning of hydrophobic organic chemicals to silicone rubber passive samplers. Environmental Science & Technology, 49, 6791-6799.
Landrum, P. F., Eadie, B. J., & Faust, W. R. (1992). Variation in the bioavailability of polycyclic aromatic hydrocarbons to the amphipod (Diporeia spp.) with sediment aging. Environmental Toxicology and Chemistry, 11, 1197-1208.
Li, H., Zhang, B., Wei, Y., Wang, F., Lydy, M. J., & You, J. (2014). Bioaccumulation of highly hydrophobic organohalogen flame retardants from sediments: Application of toxicokinetics and passive sampling techniques. Environmental Science & Technology, 48, 6957-6964.
Lydy, M. J., Landrum, P. F., Oen, A. M., Allinson, M., Smedes, F., Harwood, A. D., Li, H., Maruya, K. A., & Liu, J. (2014). Passive sampling methods for contaminated sediments: State of the science for organic contaminants. Integrated Environmental Assessment and Management, 10, 167-178.
Mackay, D., Powell, D. E., & Woodburn, K. B. (2015). Bioconcentration and aquatic toxicity of superhydrophobic chemicals: A modeling case study of cyclic volatile methyl siloxanes. Environmental Science & Technology, 49, 11913-11922.
Mayer, P., Parkerton, T. F., Adams, R. G., Cargill, J. G., Gan, J., Gouin, T., Gschwend, P. M., Hawthorne, S. B., Helm, P., Witt, G., You, J., & Escher, B. I. (2014). Passive sampling methods for contaminated sediments: Scientific rationale supporting use of freely dissolved concentrations. Integrated Environmental Assessment and Management, 10, 197-209.
Muijs, B., & Jonker, M. T. O. (2010). A closer look at bioaccumulation of petroleum hydrocarbon mixtures in aquatic worms. Environmental Toxicology and Chemistry, 29, 1943-1949.
Muijs, B., & Jonker, M. T. O. (2012). Does equilibrium passive sampling reflect actual in situ bioaccumulation of PAHs and petroleum hydrocarbon mixtures in aquatic worms? Environmental Science & Technology, 46, 937-944.
Murdoch, M. H., Chapman, P. M., Norman, D. M., & Quintino, V. M. (1997). Spiking sediment with organochlorines for toxicity testing. Environmental Toxicology and Chemistry, 16, 1504-1509.
Northcott, G. L., & Jones, K. C. (2000a). Developing a standard spiking procedure for the introduction of hydrophobic organic compounds into field-wet soil. Environmental Toxicology and Chemistry, 19, 2409-2417.
Northcott, G. L., & Jones, K. C. (2000b). Spiking hydrophobic organic compounds into soil and sediment: A review and critique of adopted procedures. Environmental Toxicology and Chemistry, 19, 2418-2430.
Organisation for Economic Co-operation and Development. (2004). Test No. 218: Sediment-water Chironomid toxicity test using spiked sediment. OECD guidelines for the testing of chemicals.
Organisation for Economic Co-operation and Development. (2007). Test No. 225: Sediment-water Lumbriculus toxicity test using spiked sediment. OECD guidelines for the testing of chemicals.
Picone, M., Distefano, G. G., Marchetto, D., Russo, M., & Volpi Ghirardini, A. (2022). Spiking organic chemicals onto sediments for ecotoxicological analyses: An overview of methods and procedures. Environmental Science and Pollution Research, 29, 31002-31024.
Redman, A. D., Parkerton, T. F., Paumen, M. L., McGrath, J. A., Den Haan, K., & Di Toro, D. M. (2014). Extension and validation of the target lipid model for deriving predicted no-effect concentrations for soils and sediments. Environmental Toxicology and Chemistry, 33, 2679-2687.
Reid, B. J., Northcott, G. L., Jones, K. C., & Semple, K. T. (1998). Evaluation of spiking procedures for the introduction of poorly water soluble contaminants into soil. Environmental Science & Technology, 32, 3224-3227.
Stibany, F., Schmidt, S. N., Schäffer, A., & Mayer, P. (2017). Aquatic toxicity testing of liquid hydrophobic chemicals-Passive dosing exactly at the saturation limit. Chemosphere, 167, 551-558.
US Environmental Protection Agency. (2000). Methods for measuring the toxicity and bioaccumulation of sediment-associated contaminants with freshwater invertebrates. EPA/600/R-99/064.
You, J., Brennan, A., & Lydy, M. J. (2009). Bioavailability and biotransformation of sediment-associated pyrethroid insecticides in Lumbriculus variegatus. Chemosphere, 75, 1477-1482.