A conserved interdomain microbial network underpins cadaver decomposition despite environmental variables.

Journal

Nature microbiology

ISSN: 2058-5276

Titre abrégé: Nat Microbiol

Pays: England

ID NLM: 101674869

Informations de publication

Date de publication:
12 Feb 2024

Historique:

received: 28 06 2023

accepted: 08 12 2023

medline: 13 2 2024

pubmed: 13 2 2024

entrez: 12 2 2024

Statut: aheadofprint

Résumé

Microbial breakdown of organic matter is one of the most important processes on Earth, yet the controls of decomposition are poorly understood. Here we track 36 terrestrial human cadavers in three locations and show that a phylogenetically distinct, interdomain microbial network assembles during decomposition despite selection effects of location, climate and season. We generated a metagenome-assembled genome library from cadaver-associated soils and integrated it with metabolomics data to identify links between taxonomy and function. This universal network of microbial decomposers is characterized by cross-feeding to metabolize labile decomposition products. The key bacterial and fungal decomposers are rare across non-decomposition environments and appear unique to the breakdown of terrestrial decaying flesh, including humans, swine, mice and cattle, with insects as likely important vectors for dispersal. The observed lockstep of microbial interactions further underlies a robust microbial forensic tool with the potential to aid predictions of the time since death.

Identifiants

DOI: 10.1038/s41564-023-01580-y PMID: 38347104

pubmed: 38347104

doi: 10.1038/s41564-023-01580-y

pii: 10.1038/s41564-023-01580-y

doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

Subventions

Organisme : United States Department of Justice | National Institute of Justice (NIJ)

ID : 2015-DN-BX-K016

Organisme : United States Department of Justice | National Institute of Justice (NIJ)

ID : 2016-DN-BX-0194

Organisme : Foundation for the National Institutes of Health (Foundation for the National Institutes of Health, Inc.)

ID : T32GM132057

Informations de copyright

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