Lipid Droplets in Virus Replication.
assembly
lipid droplet
metabolism
replication organelles
viruses
Journal
FEBS letters
ISSN: 1873-3468
Titre abrégé: FEBS Lett
Pays: England
ID NLM: 0155157
Informations de publication
Date de publication:
13 Feb 2024
13 Feb 2024
Historique:
revised:
01
12
2023
received:
28
09
2023
accepted:
10
12
2023
medline:
13
2
2024
pubmed:
13
2
2024
entrez:
13
2
2024
Statut:
aheadofprint
Résumé
Intracellular pathogens rely on host metabolic networks for multiplication. Enveloped viruses need lipids for formation of the viral envelope and positive sense RNA viruses that replicate in membranous inclusions require lipids for formation of the replication compartments. In addition, all intracellular pathogens need energy for their replicative cycle. As triglycerides in lipid droplets are the main energy storage unit of cells and major source of membrane lipids, it is not surprising that viruses have evolved various strategies to exploit different aspects of lipid droplet biology.
Identifiants
pubmed: 38348563
doi: 10.1002/1873-3468.14819
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Deutsche Forschungsgemeinschaft
ID : DFG HE 6889/5
Organisme : Deutsche Forschungsgemeinschaft
ID : CRC 2021 project B10
Organisme : LOEWE Center DRUID
Informations de copyright
© 2024 The Authors. FEBS Letters published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.