Borna disease in an adult free-ranging Eurasian beaver (Castor fiber albicus).
Borna disease
Castor fiber albicus
beaver
encephalitis
Journal
Journal of comparative pathology
ISSN: 1532-3129
Titre abrégé: J Comp Pathol
Pays: England
ID NLM: 0102444
Informations de publication
Date de publication:
12 Feb 2024
12 Feb 2024
Historique:
received:
19
10
2023
revised:
01
12
2023
accepted:
11
01
2024
medline:
14
2
2024
pubmed:
14
2
2024
entrez:
13
2
2024
Statut:
aheadofprint
Résumé
Borna disease (BD) associated with a peracute bacterial septicaemia with Escherichia coli was diagnosed in an adult female, naturally infected, free-ranging Eurasian beaver of the subspecies Castor fiber albicus, clinically characterized by weight loss, depression, weakness and gurgled peristaltic sounds. The beaver was euthanized humanely. Necropsy and light microscopy revealed a non-purulent meningoencephalitis with typical mononuclear perivascular cuffs and parenchymal infiltrates. The diagnosis of BD was confirmed by detection of viral antigen and RNA by immunohistochemistry and reverse transcription-polymerase chain reaction (RT-PCR). The PCR product was sequenced and cluster analysis revealed a close relationship between endemic clusters in Saxony-Anhalt. This is the first report of naturally occurring BD in a free-ranging Eurasian beaver.
Identifiants
pubmed: 38350270
pii: S0021-9975(24)00011-2
doi: 10.1016/j.jcpa.2024.01.003
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
31-35Informations de copyright
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