ESPEN practical short micronutrient guideline.

B-vitamins Copper Deficiency Diagnosis Iron Monitoring Prescription Selenium Thiamin Trace elements Vitamin Vitamins-A- C-D- E- K Zinc

Journal

Clinical nutrition (Edinburgh, Scotland)
ISSN: 1532-1983
Titre abrégé: Clin Nutr
Pays: England
ID NLM: 8309603

Informations de publication

Date de publication:
30 Jan 2024
Historique:
received: 10 01 2024
accepted: 27 01 2024
medline: 14 2 2024
pubmed: 14 2 2024
entrez: 13 2 2024
Statut: aheadofprint

Résumé

Trace elements and vitamins, named together micronutrients (MNs), are essential for human metabolism. The importance of MNs in common pathologies is recognized by recent research, with deficiencies significantly impacting the outcome. This short version of the guideline aims to provide practical recommendations for clinical practice. An extensive search of the literature was conducted in the databases Medline, PubMed, Cochrane, Google Scholar, and CINAHL for the initial guideline. The search focused on physiological data, historical evidence (for papers published before PubMed release in 1996), and observational and/or randomized trials. For each MN, the main functions, optimal analytical methods, impact of inflammation, potential toxicity, and provision during enteral or parenteral nutrition were addressed. The SOP wording was applied for strength of recommendations. The limited number of interventional trials prevented meta-analysis and led to a low level of evidence for most recommendations. The recommendations underwent a consensus process, which resulted in a percentage of agreement (%): strong consensus required of >90 % of votes. Altogether the guideline proposes 3 general recommendations and specific recommendations for the 26 MNs. Monitoring and management strategies are proposed. This short version of the MN guideline should facilitate handling of the MNs in at-risk diseases, whilst offering practical advice on MN provision and monitoring during nutritional support.

Sections du résumé

BACKGROUND BACKGROUND
Trace elements and vitamins, named together micronutrients (MNs), are essential for human metabolism. The importance of MNs in common pathologies is recognized by recent research, with deficiencies significantly impacting the outcome.
OBJECTIVE OBJECTIVE
This short version of the guideline aims to provide practical recommendations for clinical practice.
METHODS METHODS
An extensive search of the literature was conducted in the databases Medline, PubMed, Cochrane, Google Scholar, and CINAHL for the initial guideline. The search focused on physiological data, historical evidence (for papers published before PubMed release in 1996), and observational and/or randomized trials. For each MN, the main functions, optimal analytical methods, impact of inflammation, potential toxicity, and provision during enteral or parenteral nutrition were addressed. The SOP wording was applied for strength of recommendations.
RESULTS RESULTS
The limited number of interventional trials prevented meta-analysis and led to a low level of evidence for most recommendations. The recommendations underwent a consensus process, which resulted in a percentage of agreement (%): strong consensus required of >90 % of votes. Altogether the guideline proposes 3 general recommendations and specific recommendations for the 26 MNs. Monitoring and management strategies are proposed.
CONCLUSION CONCLUSIONS
This short version of the MN guideline should facilitate handling of the MNs in at-risk diseases, whilst offering practical advice on MN provision and monitoring during nutritional support.

Identifiants

pubmed: 38350290
pii: S0261-5614(24)00041-4
doi: 10.1016/j.clnu.2024.01.030
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

825-857

Informations de copyright

Copyright © 2024 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of interest All the authors declares no conflicts of interest.

Auteurs

Mette M Berger (MM)

Faculty of Biology & Medicine, Lausanne University, Lausanne, Switzerland. Electronic address: Mette.Berger@unil.ch.

Alan Shenkin (A)

Institute of Aging and Chronic Disease, University of Liverpool, Liverpool, UK. Electronic address: shenkin@liverpool.ac.uk.

Oguzhan Sıtkı Dizdar (OS)

Department of Internal Medicine and Clinical Nutrition Unit, University of Health Sciences Kayseri City Training and Research Hospital, Kayseri, Turkey. Electronic address: oguzhansitki.dizdar@sbu.edu.tr.

Karin Amrein (K)

Medical University of Graz, Department of Internal Medicine, Division of Endocrinology and Diabetology, Austria. Electronic address: karin.amrein@medunigraz.at.

Marc Augsburger (M)

University Centre of Legal Medicine Lausanne-Geneva, Lausanne University Hospital and University of Lausanne, Geneva University Hospital and University of Geneva, Lausanne-Geneva, Switzerland. Electronic address: Marc.Augsburger@chuv.ch.

Hans-Konrad Biesalski (HK)

Institute of Nutritional Science, University of Hohenheim, Stuttgart, Germany. Electronic address: hans-k.biesalski@uni-hohenheim.de.

Stephan C Bischoff (SC)

Institute of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany. Electronic address: bischoff.stephan@uni-hohenheim.de.

Michael P Casaer (MP)

KU Leuven, Department of Cellular and Molecular Medicine, Laboratory of Intensive Care Medicine, Leuven, Belgium. Electronic address: michael.casaer@uzleuven.be.

Kursat Gundogan (K)

Division of Intensive Care Medicine, Department of Internal Medicine, Erciyes University School of Medicine, Kayseri, Turkey. Electronic address: kursatgundogan@gmail.com.

Hanna-Liis Lepp (HL)

North Estonia Regional Hospital, Tallinn, Estonia. Electronic address: liis.lepp@gmail.com.

Angélique M E de Man (AME)

Department of Intensive Care Medicine, Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Science (ACS), Amsterdam Infection and Immunity Institute (AI&II), Amsterdam Medical Data Science (AMDS), Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands. Electronic address: ame.deman@amsterdamumc.nl.

Giovanna Muscogiuri (G)

Dipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Università di Napoli (Federico II), Naples, Italy; United Nations Educational, Scientific and Cultural Organization (UNESCO) Chair for Health Education and Sustainable Development, Federico II University, Naples, Italy. Electronic address: giovanna.muscogiuri@gmail.com.

Magdalena Pietka (M)

Pharmacy Department, Stanley Dudrick's Memorial Hospital, Skawina, Poland. Electronic address: magpietka@gmail.com.

Loris Pironi (L)

Department of Medical and Surgical Sciences, University of Bologna, Italy; Centre for Chronic Intestinal Failure, IRCCS AOUBO, Bologna, Italy. Electronic address: Loris.pironi@unibo.it.

Serge Rezzi (S)

Swiss Nutrition and Health Foundation, Epalinges, Switzerland. Electronic address: serge.rezzi@nutritionhealthfoundation.ch.

Anna Schweinlin (A)

Institute of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany. Electronic address: anna.schweinlin@uni-hohenheim.de.

Cristina Cuerda (C)

Departamento de Medicina, Universidad Complutense de Madrid, Nutrition Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain. Electronic address: cuerda.cristina@gmail.com.

Classifications MeSH