The Role of G Protein-Coupled Receptors and Receptor Kinases in Pancreatic
Journal
Pharmacological reviews
ISSN: 1521-0081
Titre abrégé: Pharmacol Rev
Pays: United States
ID NLM: 0421737
Informations de publication
Date de publication:
13 Feb 2024
13 Feb 2024
Historique:
received:
03
08
2023
revised:
01
12
2023
accepted:
07
12
2023
medline:
14
2
2024
pubmed:
14
2
2024
entrez:
13
2
2024
Statut:
epublish
Résumé
Type 2 diabetes (T2D) mellitus has emerged as a major global health concern that has accelerated in recent years due to poor diet and lifestyle. Afflicted individuals have high blood glucose levels that stem from the inability of the pancreas to make enough insulin to meet demand. Although medication can help to maintain normal blood glucose levels in individuals with chronic disease, many of these medicines are outdated, have severe side effects, and often become less efficacious over time, necessitating the need for insulin therapy. G protein-coupled receptors (GPCRs) regulate many physiologic processes, including blood glucose levels. In pancreatic
Identifiants
pubmed: 38351071
pii: pharmrev.123.001015
doi: 10.1124/pharmrev.123.001015
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
267-299Informations de copyright
Copyright © 2024 by The Author(s).