Chemokine expression profile of an innate granuloma.

Granulomas are defined by the presence of organized layers of immune cells that include macrophages. Granulomas are often characterized as a way for the immune system to contain an infection and prevent its dissemination. We recently established a mouse infection model where A successful innate granuloma requires CCR2 to organize the macrophage ring, and without CCR2, mice succumb to