Acute Thrombocytosis in a Patient Treated with Ertapenem.

Ertapenem thrombocytosis

Journal

European journal of case reports in internal medicine
ISSN: 2284-2594
Titre abrégé: Eur J Case Rep Intern Med
Pays: Italy
ID NLM: 101648453

Informations de publication

Date de publication:
2024
Historique:
received: 03 01 2024
accepted: 11 01 2024
medline: 14 2 2024
pubmed: 14 2 2024
entrez: 14 2 2024
Statut: epublish

Résumé

Ertapenem, a carbapenem-type beta-lactam antibiotic, demonstrates broad-spectrum efficacy against a wide range of Gram-positive and Gram-negative bacteria, including aerobes and anaerobes. Importantly, it demonstrates resistance to virtually all beta-lactamases, including the extended spectrum beta-lactamases (ESBLs). Haematologic complications such as thrombocytosis, haemolysis, anaemia, and neutropenia are infrequent side effects associated with this drug. In this report, we present a rare case of ertapenem-induced thrombocytosis in a 62-year-old female patient who was admitted for a complicated urinary tract infection caused by Ertapenem was identified as the most likely cause of thrombocytosis.Discontinuing ertapenem normalised the platelet count.It is crucial for physicians to identify and address causes of thrombocytosis, particularly when related to medications, to avoid inadvertent complications and to ensure effective patient care.

Identifiants

pubmed: 38352807
doi: 10.12890/2024_004283
pii: 4283
pmc: PMC10860918
doi:

Types de publication

Journal Article

Langues

eng

Pagination

004283

Informations de copyright

© EFIM 2024.

Déclaration de conflit d'intérêts

Conflicts of Interests: The Authors declare that there are no competing interests.

Auteurs

Edward K Sarfo (EK)

Icahn School of Medicine at Mount Sinai, New York, USA.

Jennifer L Dziemianko (JL)

Icahn School of Medicine at Mount Sinai, New York, USA.
NYC Health and Hospitals, Elmhurst Hospital Center, New York, USA.

Thomas Chen (T)

Icahn School of Medicine at Mount Sinai, New York, USA.

Kosuke K Iwaki (KK)

Icahn School of Medicine at Mount Sinai, New York, USA.
NYC Health and Hospitals, Elmhurst Hospital Center, New York, USA.

Classifications MeSH