Involvement of the Keap1-Nrf2-ARE pathway in the antioxidant activity of sinomenine.

In vitro antioxidant activity Keap1-Nrf2-ARE pathway Molecular mechanism Sinomenine

Journal

Archives of biochemistry and biophysics
ISSN: 1096-0384
Titre abrégé: Arch Biochem Biophys
Pays: United States
ID NLM: 0372430

Informations de publication

Date de publication:
12 Feb 2024
Historique:
received: 31 10 2023
revised: 24 01 2024
accepted: 11 02 2024
medline: 15 2 2024
pubmed: 15 2 2024
entrez: 14 2 2024
Statut: aheadofprint

Résumé

Sinomenine is a pure alkaloid isolated from Sinomenium acutum. This study is aimed to investigate the critical role of the nuclear factor erythroid 2-related factor 2 (Nrf2)-kelch-like ECH-associated protein-1(Keap1)-antioxidant response element (ARE) antioxidative signaling pathway in protecting sinomenine against H

Identifiants

DOI: 10.1016/j.abb.2024.109928 PMID: 38354876
pubmed: 38354876
pii: S0003-9861(24)00047-X
doi: 10.1016/j.abb.2024.109928
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

109928

Informations de copyright

Copyright © 2024. Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Tianzhu Guan (T)

School of Food Science and Engineering, Yangzhou University, Yangzhou, 225127, China; College of Chemistry and Environmental Science, Laboratory of Xinjiang Native Medicinal and Edible Plant Resources Chemistry, Kashi University, Kashi, 844000, China.

Ning Li (N)

School of Food Science and Engineering, Yangzhou University, Yangzhou, 225127, China.

Xiangxiu Xu (X)

Changchun Market Supervision Comprehensive Administrative Law Enforcement Detachment, Changchun, 130061, China.

Dan Xiong (D)

School of Food Science and Engineering, Yangzhou University, Yangzhou, 225127, China.

Bo Wang (B)

School of Food Science and Engineering, Yangzhou University, Yangzhou, 225127, China.

Lixia Xiao (L)

School of Food Science and Engineering, Yangzhou University, Yangzhou, 225127, China.

Weikang Yang (W)

School of Food Science and Engineering, Yangzhou University, Yangzhou, 225127, China.

Ganghui Chu (G)

College of Chemistry and Environmental Science, Laboratory of Xinjiang Native Medicinal and Edible Plant Resources Chemistry, Kashi University, Kashi, 844000, China.

Abdulla Yusuf (A)

College of Chemistry and Environmental Science, Laboratory of Xinjiang Native Medicinal and Edible Plant Resources Chemistry, Kashi University, Kashi, 844000, China.

Jie Zhang (J)

College of Food Science and Engineering, Jilin University, Changchun, 130062, China. Electronic address: zhangjie83@jlu.edu.cn.

Weiming Yue (W)

Department of Thoracic Surgery, Qilu Hospital of Shandong University, Jinan, 250012, China. Electronic address: ywmfz2013@126.com.

Classifications MeSH