Record of strep throat infections in Italy: what is needed to know about penicillin allergy? The point of view from the Italian Society of Pediatric Allergy and Immunology (SIAIP).
Amoxicillin
Drug hypersensitivity
Group A streptococcus
Immediate reactions (IRs)
Invasive group A streptococcal (iGAS) infection
Non-immediate reactions (NIRs)
Pharyngitis
Journal
Italian journal of pediatrics
ISSN: 1824-7288
Titre abrégé: Ital J Pediatr
Pays: England
ID NLM: 101510759
Informations de publication
Date de publication:
14 Feb 2024
14 Feb 2024
Historique:
received:
15
05
2023
accepted:
19
11
2023
medline:
15
2
2024
pubmed:
15
2
2024
entrez:
14
2
2024
Statut:
epublish
Résumé
Notifications of invasive group A streptococcal (iGAS) infections have significantly increased in many European Countries compared to the previous season. In Italy, there has been an increase in streptococcal pharyngitis and scarlet fever cases since January 2023, which sparked concerns about a GAS epidemic in the pediatric population. This rise may be ascribed to the GAS infection season that began earlier than usual (off-season outbreak) and the increase in the spread of respiratory viruses and viral coinfections that raised the risk of iGAS disease. Moreover, this phenomenon was also facilitated by increased travel after reduced GAS circulation during the COVID-19 pandemic.The increase in cases of GAS disease has raised some critical issues regarding the potential reactions to administering amoxicillin, the first-line antibiotic therapy, many of which have been erroneously labeled as "allergy."For these reasons, the Italian Society of Pediatric Allergy and Immunology (SIAIP) intends to provide simple clinical indications to help pediatricians manage GAS pharyngitis, discerning the allergic from non-allergic drug hypersensitivity.
Identifiants
pubmed: 38355651
doi: 10.1186/s13052-023-01561-1
pii: 10.1186/s13052-023-01561-1
doi:
Types de publication
Letter
Langues
eng
Sous-ensembles de citation
IM
Pagination
29Informations de copyright
© 2024. The Author(s).
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