First-in-Human Study of

18F-SynVesT-2 SV2A brain PET dosimetry first-in-human kinetic modeling

Journal

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
ISSN: 1535-5667
Titre abrégé: J Nucl Med
Pays: United States
ID NLM: 0217410

Informations de publication

Date de publication:
15 Feb 2024
Historique:
received: 31 07 2023
revised: 19 12 2023
medline: 16 2 2024
pubmed: 16 2 2024
entrez: 15 2 2024
Statut: aheadofprint

Résumé

PET imaging of synaptic vesicle glycoprotein 2A allows for noninvasive quantification of synapses. This first-in-human study aimed to evaluate the kinetics, test-retest reproducibility, and extent of specific binding of a recently developed synaptic vesicle glycoprotein 2A PET ligand, (

Identifiants

pubmed: 38360052
pii: jnumed.123.266470
doi: 10.2967/jnumed.123.266470
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 by the Society of Nuclear Medicine and Molecular Imaging.

Auteurs

Lindsey R Drake (LR)

Yale PET Center, New Haven, Connecticut.

Yanjun Wu (Y)

Yale PET Center, New Haven, Connecticut.

Mika Naganawa (M)

Yale PET Center, New Haven, Connecticut.

Ruth Asch (R)

Yale PET Center, New Haven, Connecticut.

Chao Zheng (C)

Yale PET Center, New Haven, Connecticut.

Soheila Najafzadeh (S)

Yale PET Center, New Haven, Connecticut.

Richard Pracitto (R)

Yale PET Center, New Haven, Connecticut.

Marcel Lindemann (M)

Yale PET Center, New Haven, Connecticut.

Songye Li (S)

Yale PET Center, New Haven, Connecticut.

Jim Ropchan (J)

Yale PET Center, New Haven, Connecticut.

David Labaree (D)

Yale PET Center, New Haven, Connecticut.

Paul R Emery (PR)

Yale PET Center, New Haven, Connecticut.

Mark Dias (M)

Yale PET Center, New Haven, Connecticut.

Shannan Henry (S)

Yale PET Center, New Haven, Connecticut.

Nabeel Nabulsi (N)

Yale PET Center, New Haven, Connecticut.

David Matuskey (D)

Yale PET Center, New Haven, Connecticut.

Ansel T Hillmer (AT)

Yale PET Center, New Haven, Connecticut.

Jean-Dominique Gallezot (JD)

Yale PET Center, New Haven, Connecticut.

Richard E Carson (RE)

Yale PET Center, New Haven, Connecticut.

Zhengxin Cai (Z)

Yale PET Center, New Haven, Connecticut henry.huang@yale.edu jason.cai@yale.edu.

Classifications MeSH