Burkitt Lymphoma Presenting as Ileocolic Intussusception in an Adult.

Adult Intussusception Burkitt Lymphoma Prognostication

Journal

Open journal of blood diseases
ISSN: 2164-3199
Titre abrégé: Open J Blood Dis
Pays: United States
ID NLM: 9918315985906676

Informations de publication

Date de publication:
Dec 2023
Historique:
medline: 16 2 2024
pubmed: 16 2 2024
entrez: 16 2 2024
Statut: ppublish

Résumé

Adult intussusception is rare, highly associated with a malignant lead point, and often requires emergent surgical management. We report the case of a 44-year-old male who presented with generalized abdominal pain and was found to have early ileocolic intussusception secondary to a large ileocecal mass. Biopsies of the mass and an enlarged cardiophrenic lymph node, as well as pleural fluid cytology were all consistent with Burkitt lymphoma (BL). Curiously, the patient's abdominal exam was reassuring, and the intussusception and malignant bowel obstruction resolved over 36 hours with conservative management alone. With a Burkitt lymphoma international prognostic index (BL-IPI) score of 2, the patient proceeded to treatment with combination chemoimmunotherapy and attained a complete response after four cycles. There was no bowel perforation or recurrent intussusception throughout treatment. Thus, this report marks the first reported case of adult BL-associated intussusception to resolve with non-invasive management and establishes a precedent for conservative management in select patients.

Identifiants

pubmed: 38361601
doi: 10.4236/ojbd.2023.134014
pmc: PMC10868555
doi:

Types de publication

Journal Article

Langues

eng

Pagination

121-132

Déclaration de conflit d'intérêts

Conflicts of Interest The authors declare no conflicts of interest regarding the publication of this paper.

Auteurs

Carla Isabel Borré (CI)

Yale School of Public Health, Yale University, New Haven, USA.

Bethany Boyle (B)

Department of Medicine, Mayo Clinic, Rochester, USA.

Kelsey Lynch (K)

Department of Medicine, Mayo Clinic, Rochester, USA.

Anuradha Kanaparthi (A)

Department of Medicine, Mayo Clinic, Rochester, USA.

Clifford Michael Csizmar (CM)

Department of Medicine, Mayo Clinic, Rochester, USA.

Daniel Philip Larson (DP)

Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, USA.

Matthew Dain Braithwaite (MD)

Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, USA.

Isla McKerrow Johnson (IM)

Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, USA.

Thomas Elmer Witzig (TE)

Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, USA.

Diego Armando Suarez (DA)

Division of Community Internal Medicine, Department of Medicine, Mayo Clinic, Rochester, USA.

Classifications MeSH