Combinations of the azaquinazoline anti-
AWZ1066S
Wolbachia
anti-Wolbachia drugs
benzimidazole
lymphatic filariasis
macrofilaricidal drugs
onchocerciasis
Journal
Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977
Informations de publication
Date de publication:
2024
2024
Historique:
received:
28
11
2023
accepted:
02
01
2024
medline:
16
2
2024
pubmed:
16
2
2024
entrez:
16
2
2024
Statut:
epublish
Résumé
Lymphatic filariasis and onchocerciasis are two major neglected tropical diseases that are responsible for causing severe disability in 50 million people worldwide, whilst veterinary filariasis (heartworm) is a potentially lethal parasitic infection of companion animals. There is an urgent need for safe, short-course curative (macrofilaricidal) drugs to eliminate these debilitating parasite infections. We investigated combination treatments of the novel anti-
Identifiants
pubmed: 38362501
doi: 10.3389/fmicb.2024.1346068
pmc: PMC10867176
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1346068Subventions
Organisme : Medical Research Council
ID : MC_PC_18055
Pays : United Kingdom
Informations de copyright
Copyright © 2024 Hegde, Marriott, Pionnier, Steven, Bulman, Gunderson, Vogel, Koschel, Ehrens, Lustigman, Voronin, Tricoche, Hoerauf, Hübner, Sakanari, Aljayyoussi, Gusovsky, Dagley, Hong, O'Neill, Ward, Taylor and Turner.
Déclaration de conflit d'intérêts
FG was employed by Eisai Co., Ltd., Tokyo, Japan. The remaining authors declare the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.
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