Prescribing trends of proton pump inhibitors and histamine blockers among children in the United Kingdom (1998-2019): A population-based assessment.
children
cohort
prescriptions proton pump inhibitors
reflux
Journal
Pharmacoepidemiology and drug safety
ISSN: 1099-1557
Titre abrégé: Pharmacoepidemiol Drug Saf
Pays: England
ID NLM: 9208369
Informations de publication
Date de publication:
Feb 2024
Feb 2024
Historique:
revised:
29
11
2023
received:
28
07
2023
accepted:
21
12
2023
medline:
16
2
2024
pubmed:
16
2
2024
entrez:
16
2
2024
Statut:
ppublish
Résumé
To describe the prescribing trends of proton pump inhibitors (PPIs) and H We conducted a population-based retrospective cohort study using data from the Clinical Practice Research Datalink that included all children aged ≤18 years with a first ever diagnosis of gastroesophageal reflux between 1998 and 2019. Using negative binomial regression, we estimated crude and adjusted annual prescription rates per 1000 person-years and corresponding 95% confidence intervals (CIs) for PPIs and H Our cohort included 177 477 children with a first ever diagnosis of gastroesophageal reflux during the study period. The median age was 13 years (IQR: 1, 17) among children prescribed PPIs and 0.2 years (IQR: 0.1, 0.6) among those prescribed H Prescription rates for PPIs increased, especially during the first half of the study period, while prescription rates for H
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e5752Informations de copyright
© 2024 The Authors. Pharmacoepidemiology and Drug Safety published by John Wiley & Sons Ltd.
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