Abdominal donor-site complications following autologous breast reconstruction: A multi-institutional multisurgeon study.

Abdominal wall Breast reconstruction Bulge Complications Deep inferior epigastric perforator flap Donor site Hernia

Journal

Journal of plastic, reconstructive & aesthetic surgery : JPRAS
ISSN: 1878-0539
Titre abrégé: J Plast Reconstr Aesthet Surg
Pays: Netherlands
ID NLM: 101264239

Informations de publication

Date de publication:
01 Feb 2024
Historique:
received: 17 10 2023
revised: 13 12 2023
accepted: 29 01 2024
medline: 17 2 2024
pubmed: 17 2 2024
entrez: 16 2 2024
Statut: aheadofprint

Résumé

The deep inferior epigastric perforator (DIEP) free flap is the gold standard procedure for autologous breast reconstruction. Although breast-related complications have been well described, donor-site complications and contributing patient risk factors are poorly understood. We examined a multi-institutional, prospectively maintained database of patients undergoing DIEP free flap breast reconstruction between 2015 and 2020. We evaluated patient demographics, operative details, and abdominal donor-site complications. Logistic regression modeling was used to predict donor-site outcomes based on patient characteristics. A total of 661 patients were identified who underwent DIEP free flap breast reconstruction across multiple institutions. Using logistic regression modeling, we found that body mass index (BMI) was an independent risk factor for umbilical complications (odds ratio [OR] 1.11, confidence interval [CI] 1.04-1.18, p = 0.001), seroma (OR 1.07, CI 1.01-1.13, p = 0.003), wound dehiscence (OR 1.10, CI 1.06-1.15, p = 0.001), and surgical site infection (OR 1.10, CI 1.05-1.15, p = 0.001) following DIEP free flap breast reconstruction. Further, immediate reconstruction decreases the risk of abdominal bulge formation (OR 0.22, CI 0.108-0.429, p = 0.001). Perforator selection was not associated with abdominal morbidity in our study population. Higher BMI is associated with increased abdominal donor-site complications following DIEP free flap breast reconstruction. Efforts to lower preoperative BMI may help decrease donor-site complications.

Sections du résumé

BACKGROUND BACKGROUND
The deep inferior epigastric perforator (DIEP) free flap is the gold standard procedure for autologous breast reconstruction. Although breast-related complications have been well described, donor-site complications and contributing patient risk factors are poorly understood.
METHODS METHODS
We examined a multi-institutional, prospectively maintained database of patients undergoing DIEP free flap breast reconstruction between 2015 and 2020. We evaluated patient demographics, operative details, and abdominal donor-site complications. Logistic regression modeling was used to predict donor-site outcomes based on patient characteristics.
RESULTS RESULTS
A total of 661 patients were identified who underwent DIEP free flap breast reconstruction across multiple institutions. Using logistic regression modeling, we found that body mass index (BMI) was an independent risk factor for umbilical complications (odds ratio [OR] 1.11, confidence interval [CI] 1.04-1.18, p = 0.001), seroma (OR 1.07, CI 1.01-1.13, p = 0.003), wound dehiscence (OR 1.10, CI 1.06-1.15, p = 0.001), and surgical site infection (OR 1.10, CI 1.05-1.15, p = 0.001) following DIEP free flap breast reconstruction. Further, immediate reconstruction decreases the risk of abdominal bulge formation (OR 0.22, CI 0.108-0.429, p = 0.001). Perforator selection was not associated with abdominal morbidity in our study population.
CONCLUSIONS CONCLUSIONS
Higher BMI is associated with increased abdominal donor-site complications following DIEP free flap breast reconstruction. Efforts to lower preoperative BMI may help decrease donor-site complications.

Identifiants

pubmed: 38364673
pii: S1748-6815(24)00032-9
doi: 10.1016/j.bjps.2024.01.033
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

88-94

Informations de copyright

Copyright © 2024. Published by Elsevier Ltd.

Auteurs

Marlie H Fisher (MH)

Department of Plastic and Reconstructive Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

Lucas B Ohmes (LB)

Department of Plastic and Reconstructive Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

Jerry H Yang (JH)

Department of Plastic and Reconstructive Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

Elliot Le (E)

Department of Plastic and Reconstructive Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

Salih Colakoglu (S)

Department of Plastic and Reconstructive Surgery, Johns Hopkins Medicine, Baltimore, MD, United States.

Mackenzie French (M)

Department of Plastic and Reconstructive Surgery, University of Washington, Seattle, WA, United States.

Duygu Siddikoglu (D)

Department of Biostatistics, Canakkale OnSekiz Mart Faculty of Medicine, Canakkale, Turkey.

Grace Um (G)

Department of Plastic and Reconstructive Surgery, University of Washington, Seattle, WA, United States.

Julian Winocour (J)

Department of Plastic and Reconstructive Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

Kent Higdon (K)

Department of Plastic and Reconstructive Surgery, Vanderbilt University Medical Center, Nashville, TN, United States.

Galen Perdikis (G)

Department of Plastic and Reconstructive Surgery, Vanderbilt University Medical Center, Nashville, TN, United States.

Suzanne Inchauste (S)

Department of Plastic and Reconstructive Surgery, University of Washington, Seattle, WA, United States.

Justin Cohen (J)

Department of Plastic and Reconstructive Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

Tae Chong (T)

Department of Plastic and Reconstructive Surgery, Virginia Commonwealth University, Richmond, VA, United States.

Christodoulos Kaoutzanis (C)

Department of Plastic and Reconstructive Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

David W Mathes (DW)

Department of Plastic and Reconstructive Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, United States. Electronic address: David.Mathes@cuanschutz.edu.

Classifications MeSH