Recurrent upper respiratory tract infections in early childhood: a newly defined clinical condition.


Journal

Italian journal of pediatrics
ISSN: 1824-7288
Titre abrégé: Ital J Pediatr
Pays: England
ID NLM: 101510759

Informations de publication

Date de publication:
16 Feb 2024
Historique:
received: 15 11 2023
accepted: 27 01 2024
medline: 17 2 2024
pubmed: 17 2 2024
entrez: 16 2 2024
Statut: epublish

Résumé

Recurrent Upper Respiratory Tract Infections (R-URTIs) pose a significant challenge in pediatric healthcare, affecting both children and their families. This study aimed to investigate the prevalence, risk factors, and clinical implications of R-URTI in children aged 0-5 years. This observational study involved a sample of 483 children aged 0-5 years, focusing on establishing a practical and dynamic definition of R-URTI. Family pediatricians prospectively collected socio-demographic information, medical history, and recorded the occurrence of URTI episodes. Children were followed from recruitment until March 2021, predating the COVID-19 outbreak. A substantial prevalence of R-URTIs was found, estimating it at 5-10% among this age group. To define R-URTI, a practical and dynamic criterion was proposed: children experiencing a minimum of four URTI episodes, each lasting four days or more, within a six-month period, with intervals of well-being in between. The study highlighted that specific risk factors for R-URTI were elusive, suggesting that this condition may affect children regardless of their family or clinical history. Moreover, the study's stratification by age group and times of observation facilitated patient-specific clinical decision-making. The proposed definition may represent a valuable tool for clinicians in diagnosing and addressing R-URTI cases.

Sections du résumé

BACKGROUND BACKGROUND
Recurrent Upper Respiratory Tract Infections (R-URTIs) pose a significant challenge in pediatric healthcare, affecting both children and their families. This study aimed to investigate the prevalence, risk factors, and clinical implications of R-URTI in children aged 0-5 years.
METHODS METHODS
This observational study involved a sample of 483 children aged 0-5 years, focusing on establishing a practical and dynamic definition of R-URTI. Family pediatricians prospectively collected socio-demographic information, medical history, and recorded the occurrence of URTI episodes. Children were followed from recruitment until March 2021, predating the COVID-19 outbreak.
RESULTS RESULTS
A substantial prevalence of R-URTIs was found, estimating it at 5-10% among this age group. To define R-URTI, a practical and dynamic criterion was proposed: children experiencing a minimum of four URTI episodes, each lasting four days or more, within a six-month period, with intervals of well-being in between.
CONCLUSIONS CONCLUSIONS
The study highlighted that specific risk factors for R-URTI were elusive, suggesting that this condition may affect children regardless of their family or clinical history. Moreover, the study's stratification by age group and times of observation facilitated patient-specific clinical decision-making. The proposed definition may represent a valuable tool for clinicians in diagnosing and addressing R-URTI cases.

Identifiants

pubmed: 38365783
doi: 10.1186/s13052-024-01600-5
pii: 10.1186/s13052-024-01600-5
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

30

Informations de copyright

© 2024. The Author(s).

Références

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Auteurs

Antonio Corsello (A)

Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy. antonio.corsello@unimi.it.
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. antonio.corsello@unimi.it.

Gregorio Paolo Milani (GP)

Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Marina Picca (M)

Italian Primary Care Paediatrics Society (SICuPP), Lombardy, Italy.

Roberto Buzzetti (R)

Clinical epidemiologist, Bergamo, Italy.

Romeo Carrozzo (R)

Italian Primary Care Paediatrics Society (SICuPP), Lombardy, Italy.

Mirko Gambino (M)

Department of Pediatrics, Vittore Buzzi Children's Hospital, Milan, Italy.

Giovanni Chiaffoni (G)

Department of Pediatrics, Vittore Buzzi Children's Hospital, Milan, Italy.

Paola Marchisio (P)

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
University of Milan, Via della Commenda 9, 20122, Milan, Italy.

Chiara Mameli (C)

Department of Pediatrics, Vittore Buzzi Children's Hospital, Milan, Italy.
Department of Biomedical and Clinical Science "L. Sacco", University of Milan, Milan, Italy.

Classifications MeSH