Macrolide and lincosamide resistance of Streptococcus agalactiae in pregnant women in Poland.
Antimicrobial susceptibility patterns
Group B Streptococcus
Lincosamide resistance
Macrolide resistance
Serotyping
Streptogramin resistance
Virulence factors
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
16 Feb 2024
16 Feb 2024
Historique:
received:
11
11
2022
accepted:
13
02
2024
medline:
17
2
2024
pubmed:
17
2
2024
entrez:
17
2
2024
Statut:
epublish
Résumé
Knowing about the antibiotic resistance, serotypes, and virulence-associated genes of Group B Streptococcus for epidemiological and vaccine development is very important. We have determined antimicrobial susceptibility patterns, serotype, and virulence profiles. The antibiotic susceptibility was assessed for a total of 421 Streptococcus agalactiae strains, isolated from pregnant women and neonates. Then, 89 erythromycin and/or clindamycin-resistant strains (82 isolates obtained from pregnant women and seven isolates derived from neonates) were assessed in detail. PCR techniques were used to identify the studied strains, perform serotyping, and assess genes encoding selected virulence factors. Phenotypic and genotypic methods determined the mechanisms of resistance. All tested strains were sensitive to penicillin and levofloxacin. The constitutive MLS
Identifiants
pubmed: 38366099
doi: 10.1038/s41598-024-54521-y
pii: 10.1038/s41598-024-54521-y
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
3877Informations de copyright
© 2024. The Author(s).
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