The reckoning of chromosomal instability: past, present, future.

Aneuploidy CIN Cancer Cytogenetics Genomic instability Quantitative measures

Journal

Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology
ISSN: 1573-6849
Titre abrégé: Chromosome Res
Pays: Netherlands
ID NLM: 9313452

Informations de publication

Date de publication:
17 Feb 2024
Historique:
received: 11 01 2024
accepted: 27 01 2024
revised: 11 01 2024
medline: 17 2 2024
pubmed: 17 2 2024
entrez: 17 2 2024
Statut: epublish

Résumé

Quantitative measures of CIN are crucial to our understanding of its role in cancer. Technological advances have changed the way CIN is quantified, offering increased accuracy and insight. Here, we review measures of CIN through its rise as a field, discuss considerations for its measurement, and look forward to future quantification of CIN.

Identifiants

pubmed: 38367036
doi: 10.1007/s10577-024-09746-y
pii: 10.1007/s10577-024-09746-y
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2

Subventions

Organisme : NIH HHS
ID : F31CA254247
Pays : United States
Organisme : NIH HHS
ID : T32CA009135
Pays : United States
Organisme : NIH HHS
ID : 1R01CA234904
Pays : United States

Informations de copyright

© 2024. The Author(s), under exclusive licence to Springer Nature B.V.

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Auteurs

Andrew Lynch (A)

UW Carbone Cancer Center, University of Wisconsin, Madison, WI, USA.
McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, WI, USA.
Division of Hematology/Oncology, Department of Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.

Shermineh Bradford (S)

UW Carbone Cancer Center, University of Wisconsin, Madison, WI, USA.
McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, WI, USA.
Division of Hematology/Oncology, Department of Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.

Mark E Burkard (ME)

UW Carbone Cancer Center, University of Wisconsin, Madison, WI, USA. mburkard@wisc.edu.
McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, WI, USA. mburkard@wisc.edu.
Division of Hematology/Oncology, Department of Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA. mburkard@wisc.edu.

Classifications MeSH