The fixation of complement protein pairs to CR2 isoforms.
Ag/Ab complexes
C3
C3b
CD21
CR2
Journal
Biochemistry and biophysics reports
ISSN: 2405-5808
Titre abrégé: Biochem Biophys Rep
Pays: Netherlands
ID NLM: 101660999
Informations de publication
Date de publication:
Jul 2024
Jul 2024
Historique:
received:
30
11
2023
revised:
26
01
2024
accepted:
27
01
2024
medline:
19
2
2024
pubmed:
19
2
2024
entrez:
19
2
2024
Statut:
epublish
Résumé
Reviewing old protocols, it was found that Raji, a CR2-posistive cell line, binds both endogenous (e-C3) and exogenous C3 (i-C3). The processing of i-C3 to an i-C3b-like protein and their fixation to CR2 isoforms resulted in the formation of heterodimers whose units might be linked via thioester by low m.w. molecule(s). In an attempt to study the origin of the low m.w. molecules, it was found that they were detected following I
Identifiants
pubmed: 38371315
doi: 10.1016/j.bbrep.2024.101657
pii: S2405-5808(24)00021-9
pmc: PMC10869749
doi:
Types de publication
Journal Article
Langues
eng
Pagination
101657Informations de copyright
© 2024 The Author.
Déclaration de conflit d'intérêts
The author declares that he has no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.