Modulation of prostaglandin transport activity of SLCO2A1 by annexin A2 and S100A10.
S100A10
SLCO2A1
annexin A2
maxi-anion channel (Maxi-Cl)
prostaglandin transporter
Journal
American journal of physiology. Cell physiology
ISSN: 1522-1563
Titre abrégé: Am J Physiol Cell Physiol
Pays: United States
ID NLM: 100901225
Informations de publication
Date de publication:
19 Feb 2024
19 Feb 2024
Historique:
medline:
19
2
2024
pubmed:
19
2
2024
entrez:
19
2
2024
Statut:
aheadofprint
Résumé
Solute carrier organic anion transporter family member 2A1 (SLCO2A1) is a prostaglandin (PG) transporter and serves as the osmosensitive ATP-permeable maxi-anion channel (Maxi-Cl). Since a heterotetrameric complex of annexin A2 (ANXA2) and S100A10 is obligatory for the channel activity; the present study aimed to determine if they regulate SLCO2A1-mediated PG transport. This study examined PGE
Identifiants
pubmed: 38372137
doi: 10.1152/ajpcell.00701.2023
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : MEXT | Japan Society for the Promotion of Science (JSPS)
ID : 22K15295
Organisme : MEXT | Japan Society for the Promotion of Science (JSPS)
ID : 20K07018
Organisme : Takasaki University of Health and Welfare
Organisme : Japan Tobacco Inc.