A single cell atlas of frozen shoulder capsule identifies features associated with inflammatory fibrosis resolution.


Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
19 Feb 2024
Historique:
received: 31 03 2023
accepted: 19 01 2024
medline: 21 2 2024
pubmed: 20 2 2024
entrez: 19 2 2024
Statut: epublish

Résumé

Frozen shoulder is a spontaneously self-resolving chronic inflammatory fibrotic human disease, which distinguishes the condition from most fibrotic diseases that are progressive and irreversible. Using single-cell analysis, we identify pro-inflammatory MERTK

Identifiants

pubmed: 38374174
doi: 10.1038/s41467-024-45341-9
pii: 10.1038/s41467-024-45341-9
pmc: PMC10876649
doi:

Substances chimiques

c-Mer Tyrosine Kinase EC 2.7.10.1

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1394

Subventions

Organisme : Medical Research Council
ID : MR/S025308/1
Pays : United Kingdom
Organisme : Versus Arthritis
ID : 22272
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/V036998/1
Pays : United Kingdom
Organisme : Versus Arthritis
ID : 22253
Pays : United Kingdom

Investigateurs

Amar Rangan (A)
Stephen Gwilym (S)
Christopher Little (C)
Andrew Titchener (A)
Salma Chaudhury (S)
Philip Holland (P)
Kim Wheway (K)
Bridget Watkins (B)
Debra Beazley (D)
Lois Vesty-Edwards (L)
Louise Appleton (L)
Marc Atkinson (M)
Lucksy Kottam (L)
Juliet James (J)
Natalie Clark (N)

Informations de copyright

© 2024. The Author(s).

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Auteurs

Michael T H Ng (MTH)

University of Oxford, Oxford, UK. michael.ng@ndorms.ox.ac.uk.

Rowie Borst (R)

University of Oxford, Oxford, UK.

Hamez Gacaferi (H)

University of Oxford, Oxford, UK.

Sarah Davidson (S)

University of Oxford, Oxford, UK.

Jessica E Ackerman (JE)

University of Oxford, Oxford, UK.

Peter A Johnson (PA)

University of Oxford, Oxford, UK.

Caio C Machado (CC)

University of Oxford, Oxford, UK.
University of Sao Paulo, Sao Paulo, Brazil.

Ian Reekie (I)

University of Oxford, Oxford, UK.

Moustafa Attar (M)

University of Oxford, Oxford, UK.

Dylan Windell (D)

University of Oxford, Oxford, UK.

Mariola Kurowska-Stolarska (M)

Research into Inflammatory Arthritis Centre Versus Arthritis (RACE), University of Glasgow, Glasgow, UK.

Lucy MacDonald (L)

Research into Inflammatory Arthritis Centre Versus Arthritis (RACE), University of Glasgow, Glasgow, UK.

Stefano Alivernini (S)

Fondazione Policlinico Universitario Agostino Gemelli - IRCCS, Rome, Italy.

Micon Garvilles (M)

University of Oxford, Oxford, UK.

Kathrin Jansen (K)

University of Oxford, Oxford, UK.

Ananya Bhalla (A)

University of Oxford, Oxford, UK.

Angela Lee (A)

University of Oxford, Oxford, UK.

James Charlesworth (J)

University of Oxford, Oxford, UK.

Rajat Chowdhury (R)

University of Oxford, Oxford, UK.

Paul Klenerman (P)

University of Oxford, Oxford, UK.

Kate Powell (K)

University of Oxford, Oxford, UK.

Dominic Furniss (D)

University of Oxford, Oxford, UK.

Jonathan Rees (J)

University of Oxford, Oxford, UK.

Derek Gilroy (D)

University College London, London, UK.

Mark Coles (M)

University of Oxford, Oxford, UK.

Andrew J Carr (AJ)

University of Oxford, Oxford, UK.

Stephen N Sansom (SN)

University of Oxford, Oxford, UK.

Stephanie G Dakin (SG)

University of Oxford, Oxford, UK. stephanie.dakin@ndorms.ox.ac.uk.

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Classifications MeSH