An Approach to the Investigation of Thrombocytosis: Differentiating between Essential Thrombocythemia and Secondary Thrombocytosis.
Journal
Advances in hematology
ISSN: 1687-9104
Titre abrégé: Adv Hematol
Pays: United States
ID NLM: 101504271
Informations de publication
Date de publication:
2024
2024
Historique:
received:
06
12
2023
revised:
24
01
2024
accepted:
05
02
2024
medline:
20
2
2024
pubmed:
20
2
2024
entrez:
20
2
2024
Statut:
epublish
Résumé
Thrombocytosis is a common reason for referral to Hematology. Differentiating between secondary causes of thrombocytosis and essential thrombocythemia (ET) is often clinically challenging. A practical diagnostic approach to identify secondary thrombocytosis could reduce overinvestigation such as next generation sequencing (NGS) panel. All adult patients with thrombocytosis (≥450 × 10 A practical approach to investigating patients with persistent thrombocytosis based on clinical characteristics such as active malignancy, chronic inflammatory disease, splenectomy, and iron deficiency may assist in accurately identifying patients more likely to have secondary causes of thrombocytosis and reduce overinvestigation, particularly costly molecular testing.
Sections du résumé
Background
UNASSIGNED
Thrombocytosis is a common reason for referral to Hematology. Differentiating between secondary causes of thrombocytosis and essential thrombocythemia (ET) is often clinically challenging. A practical diagnostic approach to identify secondary thrombocytosis could reduce overinvestigation such as next generation sequencing (NGS) panel.
Methods and Results
UNASSIGNED
All adult patients with thrombocytosis (≥450 × 10
Conclusion
UNASSIGNED
A practical approach to investigating patients with persistent thrombocytosis based on clinical characteristics such as active malignancy, chronic inflammatory disease, splenectomy, and iron deficiency may assist in accurately identifying patients more likely to have secondary causes of thrombocytosis and reduce overinvestigation, particularly costly molecular testing.
Identifiants
pubmed: 38375212
doi: 10.1155/2024/3056216
pmc: PMC10876298
doi:
Types de publication
Journal Article
Langues
eng
Pagination
3056216Informations de copyright
Copyright © 2024 Ala Almanaseer et al.
Déclaration de conflit d'intérêts
The authors declare that they have no conflicts of interest.