Long-term prognostic implications of CT angiography-derived fractional flow reserve: Results from the DISCOVER-FLOW study.
Coronary CT angiography
Fractional flow reserve
Long-term outcome
Non-invasive imaging
Risk stratification
Journal
Journal of cardiovascular computed tomography
ISSN: 1876-861X
Titre abrégé: J Cardiovasc Comput Tomogr
Pays: United States
ID NLM: 101308347
Informations de publication
Date de publication:
19 Feb 2024
19 Feb 2024
Historique:
received:
05
11
2023
revised:
08
01
2024
accepted:
26
01
2024
medline:
21
2
2024
pubmed:
21
2
2024
entrez:
20
2
2024
Statut:
aheadofprint
Résumé
The long-term prognostic implications of CT angiography-derived fractional flow reserve (FFR A total of 156 vessels from 102 patients with stable coronary artery disease, who underwent coronary CT angiography (CCTA) and invasive FFR measurement, were followed. The primary endpoint was target vessel failure (TVF), including cardiovascular death, target vessel myocardial infarction, and target vessel revascularization. Outcome analysis with FFR During median 9.9 years of follow-up, TVF occurred in 20 (12.8%) vessels. FFR FFR NCT01189331.
Sections du résumé
BACKGROUND & OBJECTIVES
OBJECTIVE
The long-term prognostic implications of CT angiography-derived fractional flow reserve (FFR
MATERIALS & METHODS
METHODS
A total of 156 vessels from 102 patients with stable coronary artery disease, who underwent coronary CT angiography (CCTA) and invasive FFR measurement, were followed. The primary endpoint was target vessel failure (TVF), including cardiovascular death, target vessel myocardial infarction, and target vessel revascularization. Outcome analysis with FFR
RESULTS
RESULTS
During median 9.9 years of follow-up, TVF occurred in 20 (12.8%) vessels. FFR
CONCLUSION
CONCLUSIONS
FFR
CLINICAL TRIAL REGISTRATION
BACKGROUND
NCT01189331.
Identifiants
pubmed: 38378313
pii: S1934-5925(24)00027-3
doi: 10.1016/j.jcct.2024.01.016
pii:
doi:
Banques de données
ClinicalTrials.gov
['NCT01189331']
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024. Published by Elsevier Inc.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interest: BKK received research grants from Abbott, Philips, and HeartFlow, provided to the Seoul National University. JL holds stock options in and serves as a consultant to HeartFlow and Circle CVI, and has a research grant from GE Healthcare. GC, MS, CZ, and CAT are the employees and shareholders of HeartFlow, Inc.