Insulin therapy among diabetic patients in rural communities of Sub-Saharan Africa: a perspective review.

glucagon glycated hemoglobin hyperglycemia hypoglycemia insulin oral hypoglycemics sub-Saharan Africa

Journal

Therapeutic advances in endocrinology and metabolism
ISSN: 2042-0188
Titre abrégé: Ther Adv Endocrinol Metab
Pays: United States
ID NLM: 101532143

Informations de publication

Date de publication:
2024
Historique:
received: 18 08 2023
accepted: 24 01 2024
medline: 21 2 2024
pubmed: 21 2 2024
entrez: 21 2 2024
Statut: epublish

Résumé

In this perspective review, we describe a brief background on the status quo of diabetes mellitus-related therapies and glycemic control among patients in rural communities in sub-Saharan Africa. The article discusses insulin therapy as well as the difficulties in obtaining insulin and oral hypoglycemic medications for diabetic patients living in sub-Saharan Africa. We wrap up our discussion with suggestions on solutions and opportunities for future research to tackle this health challenge in these impoverished communities. We conducted a literature search from PubMed and Google Scholar up until August 2023. Key words were used to generate search terms used to retrieve the required information. All types of literature with pertinent information on the current topic were included in the study. Diabetes mellitus is on the rise in sub-Saharan Africa. Several studies have reported poor glycemic control, low screening rates for diabetes mellitus, cigarette smoking, high alcohol consumption, prescription of antidiabetic therapy, and associated costs as contributors to the uptake of antidiabetic treatment. Although there is paucity of data on the extent of insulin therapy uptake and its possible modifiable contributors among the diabetic patients in the region, the anticipated increase in the number of people with diabetes on the continent makes it critical for global leaders to address the research gaps in insulin therapy among rural communities of sub-Saharan Africa, thus reducing the burden of diabetes in these populations.

Identifiants

pubmed: 38379780
doi: 10.1177/20420188241232280
pii: 10.1177_20420188241232280
pmc: PMC10878220
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

20420188241232280

Informations de copyright

© The Author(s), 2024.

Déclaration de conflit d'intérêts

The authors declare that there is no conflict of interest.

Auteurs

Ritah Kiconco (R)

Department of Medical Laboratory Science, Mbarara University of Science and Technology, Mbarara City, Mbarara-Kabale Road, Mbarara 1410, Uganda.
Department of Biochemistry, Sororti University, Soroti, Uganda.

Sylvia Achieng Lumumba (SA)

Department of Medical Laboratory Science, Mbarara University of Science and Technology, Mbarara, Uganda.
Department of Medical Laboratory Science, Technical University of Mombasa, Mombasa, Kenya.

Charles Nkubi Bagenda (CN)

Department of Medical Laboratory Science, Mbarara University of Science and Technology, Mbarara, Uganda.

Raymond Atwine (R)

Department of Pathology, Mbarara University of Science and Technology, Mbarara, Uganda.

Joseph Ndarubweine (J)

Department of Medical Laboratory Science, Mbarara University of Science and Technology, Mbarara, Uganda.

Simon Peter Rugera (SP)

Department of Medical Laboratory Science, Mbarara University of Science and Technology, Mbarara, Uganda.

Classifications MeSH