Impact of comorbidities and body mass index on the outcomes of allogeneic hematopoietic cell transplantation in myelofibrosis: A study on behalf of the Chronic Malignancies Working Party of EBMT.


Journal

American journal of hematology
ISSN: 1096-8652
Titre abrégé: Am J Hematol
Pays: United States
ID NLM: 7610369

Informations de publication

Date de publication:
22 Feb 2024
Historique:
revised: 07 02 2024
received: 26 12 2023
accepted: 08 02 2024
medline: 22 2 2024
pubmed: 22 2 2024
entrez: 22 2 2024
Statut: aheadofprint

Résumé

Investigating the evaluation of eligibility for transplant in myelofibrosis (MF): The role of HCT-CI and BMI. HCT-CI emerges as a key prognostic factor, while BMI shows limited impact. This study expands insights for better clinical decision-making in MF allo-HCT.

Identifiants

pubmed: 38385579
doi: 10.1002/ajh.27262
doi:

Types de publication

Letter

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 Wiley Periodicals LLC.

Références

Acosta-Medina AA, Baranwal A, Johnson IM, et al. Comparison of Pretransplantation prediction models for nonrelapse mortality in patients with myelofibrosis undergoing allogeneic stem cell transplantation. Transplant Cell Ther. 2023;29(6):360.e1-360.e8.
Kröger N, Bacigalupo A, Barbui T, et al. Indication and management of allogeneic haematopoietic stem-cell transplantation in myelofibrosis: updated recommendations by the EBMT/ELN International Working Group. Lancet Haematol. 2024;11(1):e62-e74.
Polverelli N, Mauff K, Kroger N, et al. Impact of spleen size and splenectomy on outcomes of allogeneic hematopoietic cell transplantation for myelofibrosis: a retrospective analysis by the chronic malignancies working party on behalf of European Society for Blood and Marrow Transplantation (EBMT). Am J Hematol. 2021;96(1):69-79.
Polverelli N, Tura P, Battipaglia G, et al. Multidimensional geriatric assessment for elderly hematological patients (≥60 years) submitted to allogeneic stem cell transplantation. A French-Italian 10-year experience on 228 patients. Bone Marrow Transplant. 2020;55(12):2224-2233.
Sorror ML, Maris MB, Storb R, et al. Hematopoietic cell transplantation (HCT)-specific comorbidity index: a new tool for risk assessment before allogeneic HCT. Blood. 2005;106(8):2912-2919.
Polverelli N, Hernandez-Boluda JC, Czerw T, et al. Splenomegaly in patients with primary or secondary myelofibrosis who are candidates for allogeneic hematopoietic cell transplantation: a Position Paper on behalf of the Chronic Malignancies Working Party of the EBMT. Lancet Haematol. 2023;10(1):e59-e70.

Auteurs

Nicola Polverelli (N)

Unit of Bone Marrow Transplantation, Division of Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

Edouard F Bonneville (EF)

Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.
EBMT Leiden Study Unit, Leiden, The Netherlands.

Liesbeth C de Wreede (LC)

Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.

Linda Koster (L)

EBMT Leiden Study Unit, Leiden, The Netherlands.

Nicolaus Martin Kröger (NM)

Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Thomas Schroeder (T)

Department of Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital of Essen, Essen, Germany.

Régis Peffault de Latour (R)

BMT Unit, Saint-Louis Hospital, Paris, France.

Jakob Passweg (J)

Hematology Division, University Hospital, Basel, Switzerland.

Katja Sockel (K)

Universitaetsklinikum Dresden, Dresden, Germany.

Annoek E C Broers (AEC)

Erasmus MC Cancer Institute, Rotterdam, The Netherlands.

Andrew Clark (A)

Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom.

Peter Dreger (P)

University of Heidelberg, Heidelberg, Germany.

Didier Blaise (D)

Programme de Transplantation & Therapie Cellulaire, Marseille, France.

Ibrahim Yakoub-Agha (I)

CHU de Lille, Lille, France.

Soeren Lykke Petersen (SL)

Bone Marrow Transplant Unit, Department of Hematology, Copenhagen University Hospital, Copenhagen, Denmark.

Jürgen Finke (J)

Department of Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Grzegorz Helbig (G)

Department of Hematology and Bone Marrow Transplantation, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.

Werner Rabitsch (W)

BMT Unit, Internal Medicine I, Medical University of Vienna, Vienna, Austria.

Simona Sammassimo (S)

Onco-Hematology Division, IEO, European Institute of Oncology IRCCS, Milan, Italy.

Luca Arcaini (L)

Unit of Bone Marrow Transplantation, Division of Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Department of Molecular Medicine, University of Pavia, Pavia, Italy.

Domenico Russo (D)

Unit of Blood Diseases and Stem Cell Transplantation, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.

Joanna Drozd-Sokolowska (J)

University Clinical Centre, Medical University of Warsaw, Warsaw, Poland.

Kavita Raj (K)

Department of Haematology and Stem Cell Transplantation, University College London Hospitals NHS Trust, London, UK.

Marie Robin (M)

BMT Unit, Saint-Louis Hospital, Paris, France.

Giorgia Battipaglia (G)

Hematology and Bone Marrow Transplantation Unit, Hematology Department, Federico II University of Naples, Naples, Italy.

Tomasz Czerw (T)

Department of Hematology, Maria Skłodowska-Curie National Research Institute of Oncology, Gliwice, Poland.

Juan Carlos Hernández-Boluda (JC)

Department of Hematology, Hospital Clínico Universitario, Valencia, Spain.

Donal P McLornan (DP)

Department of Haematology and Stem Cell Transplantation, University College London Hospitals NHS Trust, London, UK.

Classifications MeSH