Real-life practice of reflectance confocal microscopy in France: A prospective multicenter study.
Basal cell carcinoma
Confocal microscopy
Dermatopathology
Lentigo/Lentigo maligna
Melanoma
Public Health
Journal
Journal of the American Academy of Dermatology
ISSN: 1097-6787
Titre abrégé: J Am Acad Dermatol
Pays: United States
ID NLM: 7907132
Informations de publication
Date de publication:
20 Feb 2024
20 Feb 2024
Historique:
received:
27
07
2023
revised:
03
12
2023
accepted:
10
01
2024
medline:
23
2
2024
pubmed:
23
2
2024
entrez:
22
2
2024
Statut:
aheadofprint
Résumé
Studies demonstrating the potential utility of reflectance confocal microscopy (RCM) have been performed under experimental conditions. To provide an overview of RCM practice in real-life. A multicenter, prospective study carried out in 10 university dermatology departments in France. 0verall, 410 patients were enrolled. Half of the patients (48%) were referred by private-practice dermatologists. They were referred for diagnosis (84.9%) or pre-surgical mapping (13%). For diagnosis, the lesions were located on the face (62%), arms and legs (14.9%), and trunk (13,6%), and pre-surgical mapping was almost exclusively on the face (90.9%). Among those referred for diagnosis, the main indication was suspicion of a skin tumor (92.8%). Of these,50.6% were spared biopsies after RCM. When RCM indicated surgery, histology revealed malignant lesions in 72.7% of cases. The correlation between RCM and histopathology was high, with a correlation rate of 82.76% and a kappa coefficient of 0.73 (0.63; 0.82). This study was performed in the settings of French tertiary referral hospitals. This study shows that in real-life RCM can be integrated into the workflow of a public private network, which enables a less invasive diagnostic procedure for patients.
Sections du résumé
BACKGROUND
BACKGROUND
Studies demonstrating the potential utility of reflectance confocal microscopy (RCM) have been performed under experimental conditions.
OBJECTIVE
OBJECTIVE
To provide an overview of RCM practice in real-life.
METHODS
METHODS
A multicenter, prospective study carried out in 10 university dermatology departments in France.
RESULTS
RESULTS
0verall, 410 patients were enrolled. Half of the patients (48%) were referred by private-practice dermatologists. They were referred for diagnosis (84.9%) or pre-surgical mapping (13%). For diagnosis, the lesions were located on the face (62%), arms and legs (14.9%), and trunk (13,6%), and pre-surgical mapping was almost exclusively on the face (90.9%). Among those referred for diagnosis, the main indication was suspicion of a skin tumor (92.8%). Of these,50.6% were spared biopsies after RCM. When RCM indicated surgery, histology revealed malignant lesions in 72.7% of cases. The correlation between RCM and histopathology was high, with a correlation rate of 82.76% and a kappa coefficient of 0.73 (0.63; 0.82).
LIMITATIONS
CONCLUSIONS
This study was performed in the settings of French tertiary referral hospitals.
CONCLUSION
CONCLUSIONS
This study shows that in real-life RCM can be integrated into the workflow of a public private network, which enables a less invasive diagnostic procedure for patients.
Identifiants
pubmed: 38387851
pii: S0190-9622(24)00383-9
doi: 10.1016/j.jaad.2024.01.079
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024. Published by Elsevier Inc.