Improving the modelling of a multi-leaf collimator with tilted leaf sides used in radiotherapy.

MLC modelling TPS commissioning TPS modelling

Journal

Physics and imaging in radiation oncology
ISSN: 2405-6316
Titre abrégé: Phys Imaging Radiat Oncol
Pays: Netherlands
ID NLM: 101704276

Informations de publication

Date de publication:
Jan 2024
Historique:
received: 11 12 2023
revised: 24 01 2024
accepted: 25 01 2024
medline: 23 2 2024
pubmed: 23 2 2024
entrez: 23 2 2024
Statut: epublish

Résumé

Multi-leaf collimators (MLCs) with tilted leaf sides have a complex transmission behaviour that is not easily matched by radiotherapy treatment planning systems (TPSs). We sought to develop an MLC model that can accurately match test fields and clinically relevant plans at different centres. Two new MLC models were developed and evaluated within a research version of a commercial TPS. Prototype I used adjusted-constant transmissions and Prototype II used variable transmissions at the tongue-and-groove and leaf-tip regions. Three different centres evaluated these prototypes for a tilted MLC and compared them with their initial MLC model using test fields and patient-specific quality-assurance measurements of clinically relevant plans. For the latter, gamma passing rates (GPR) at 2 %/2mm were recorded. For the prototypes the same set of MLC parameters could be used at all centres, with only a slight adjustment of the offset parameter. For centres A and C, average GPR were >95 % and within 0.5 % GPR difference between the standard, and prototype models. In center B, prototypes I and II improved the agreement in clinically relevant plans, with an increase in GPR of 2.3 % ± 0.8 % and 3.0 ± 0.8 %, respectively. The prototype MLC models were either similar or superior to the initial MLC model, and simpler to configure because fewer trade-offs were required. Prototype I performed comparably to the more sophisticated Prototype II and its configuration can be easily standardized, which can be useful to reduce variability and improve safety in clinical practice.

Sections du résumé

Background and purpose UNASSIGNED
Multi-leaf collimators (MLCs) with tilted leaf sides have a complex transmission behaviour that is not easily matched by radiotherapy treatment planning systems (TPSs). We sought to develop an MLC model that can accurately match test fields and clinically relevant plans at different centres.
Materials and methods UNASSIGNED
Two new MLC models were developed and evaluated within a research version of a commercial TPS. Prototype I used adjusted-constant transmissions and Prototype II used variable transmissions at the tongue-and-groove and leaf-tip regions. Three different centres evaluated these prototypes for a tilted MLC and compared them with their initial MLC model using test fields and patient-specific quality-assurance measurements of clinically relevant plans. For the latter, gamma passing rates (GPR) at 2 %/2mm were recorded.
Results UNASSIGNED
For the prototypes the same set of MLC parameters could be used at all centres, with only a slight adjustment of the offset parameter. For centres A and C, average GPR were >95 % and within 0.5 % GPR difference between the standard, and prototype models. In center B, prototypes I and II improved the agreement in clinically relevant plans, with an increase in GPR of 2.3 % ± 0.8 % and 3.0 ± 0.8 %, respectively.
Conclusions UNASSIGNED
The prototype MLC models were either similar or superior to the initial MLC model, and simpler to configure because fewer trade-offs were required. Prototype I performed comparably to the more sophisticated Prototype II and its configuration can be easily standardized, which can be useful to reduce variability and improve safety in clinical practice.

Identifiants

pubmed: 38390588
doi: 10.1016/j.phro.2024.100543
pii: S2405-6316(24)00013-7
pmc: PMC10881418
doi:

Types de publication

Journal Article

Langues

eng

Pagination

100543

Informations de copyright

© 2024 The Author(s).

Déclaration de conflit d'intérêts

The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: NPL authors report institutional collaboration agreement with RaySearch Laboratories. Agnes Angerud is an employee of RaySearch Laboratories. The remaining authors have nothing to disclose.

Auteurs

Mohammad Hussein (M)

Metrology for Medical Physics Centre, National Physical Laboratory, Teddington, UK.

Agnes Angerud (A)

RaySearch Laboratories AB, Stockholm, Sweden.

Jordi Saez (J)

Department of Radiation Oncology, Hospital Clínic de Barcelona, Barcelona, Spain.

Evelien Bogaert (E)

Department of Radiation Oncology, Ghent University Hospital, Belgium.

Matthieu Lemire (M)

CIUSSS de l'Est-de-l'Île-de-Montréal, Quebec, Canada.

Miriam Barry (M)

Metrology for Medical Physics Centre, National Physical Laboratory, Teddington, UK.

Ileana Silvestre Patallo (I)

Metrology for Medical Physics Centre, National Physical Laboratory, Teddington, UK.

David Shipley (D)

Metrology for Medical Physics Centre, National Physical Laboratory, Teddington, UK.

Catharine H Clark (CH)

Metrology for Medical Physics Centre, National Physical Laboratory, Teddington, UK.
Medical Physics, University College London Hospital, London, UK.
Medical Physics and Bioengineering, University College London, London, UK.

Victor Hernandez (V)

Department of Medical Physics, Hospital Sant Joan de Reus, IISPV, Tarragona, Spain.
Universitat Rovira i Virgili, Tarragona, Spain.

Classifications MeSH