Improved resolution of 3-mercaptopropionate dioxygenase active site provided by ENDOR spectroscopy offers insight into catalytic mechanism.

(1)H Mims ENDOR DFT Thiol dioxygenase computational hydrogen bonding mononuclear non-heme iron pulsed EPR spectroscopy sulfur-oxidation

Journal

The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R

Informations de publication

Date de publication:
21 Feb 2024
Historique:
received: 28 11 2023
revised: 13 02 2024
accepted: 15 02 2024
medline: 24 2 2024
pubmed: 24 2 2024
entrez: 23 2 2024
Statut: aheadofprint

Résumé

3-mercaptopropionate (3MPA) dioxygenase (MDO) is a mononuclear non-heme iron enzyme that catalyzes the O

Identifiants

pubmed: 38395308
pii: S0021-9258(24)00153-4
doi: 10.1016/j.jbc.2024.105777
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

105777

Informations de copyright

Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

CONFLICT OF INTEREST The authors declare that they have no conflicts of interest with the contents of this article.

Auteurs

Brad S Pierce (BS)

Department of Chemistry & Biochemistry, University of Alabama, 250 Hackberry Lane, Tuscaloosa, Alabama 35487, United States. Electronic address: bspierce1@ua.edu.

Allison N Schmittou (AN)

Department of Chemistry & Biochemistry, University of Alabama, 250 Hackberry Lane, Tuscaloosa, Alabama 35487, United States.

Nicholas J York (NJ)

Department of Chemistry & Biochemistry, University of Alabama, 250 Hackberry Lane, Tuscaloosa, Alabama 35487, United States.

Ryan P Madigan (RP)

Department of Chemistry & Biochemistry, The University of Texas at Arlington, 700 Planetarium Place, Arlington, TX 76019 United States.

Paula F Nino (PF)

Department of Chemistry & Biochemistry, The University of Texas at Arlington, 700 Planetarium Place, Arlington, TX 76019 United States.

Frank W Foss (FW)

Department of Chemistry & Biochemistry, The University of Texas at Arlington, 700 Planetarium Place, Arlington, TX 76019 United States.

Molly M Lockart (MM)

Department of Chemistry and Biochemistry, Samford University, 800 Lakeshore Drive, Homewood, AL 35229, United States. Electronic address: mlockart@samford.edu.

Classifications MeSH