Variation in communication of side effects in prostate cancer treatment consultations.


Journal

Prostate cancer and prostatic diseases
ISSN: 1476-5608
Titre abrégé: Prostate Cancer Prostatic Dis
Pays: England
ID NLM: 9815755

Informations de publication

Date de publication:
23 Feb 2024
Historique:
received: 22 07 2023
accepted: 06 02 2024
revised: 29 01 2024
medline: 24 2 2024
pubmed: 24 2 2024
entrez: 23 2 2024
Statut: aheadofprint

Résumé

Effective communication of treatment side effects (SE) is critical for shared decision-making (SDM) in localized prostate cancer. We sought to qualitatively characterize how physicians communicate SE in consultations. We transcribed 50 initial prostate cancer treatment consultations across nine multidisciplinary providers (Urologists, Radiation Oncologists, Medical Oncologists) at our tertiary referral, academic center. Coders identified quotes describing SE and used an inductive approach to establish a hierarchy for granularity of communication: (1) not mentioned, (2) name only, (3) generalization("high"), (4) average incidence without timepoint, (5) average incidence with timepoint, and (6) precision estimate. We reported the most granular mode of communication for each SE throughout the consultation overall and across specialty and tumor risk. Among consultations discussing surgery (n = 40), erectile dysfunction (ED) and urinary incontinence (UI) were omitted in 15% and 12%, not quantified (name only or generalization) in 47% and 30%, and noted as average incidence without timeline in 8% and 8%, respectively. In only 30% and 49% were ED and UI quantified with timeline (average incidence with timeline or precision estimate), respectively. Among consultations discussing radiation (n = 36), irritative urinary symptoms, ED, and other post-radiotherapy SE were omitted in 22%, 42%, and 64-67%, not quantified in 61%, 33%, and 23-28%, and noted as average incidence without timeline in 8%, 22%, and 6-8%, respectively. In only 3-8% were post-radiotherapy SE quantified with timeline. Specialty concordance (but not tumor risk) was associated with higher granularity of communication, though physicians frequently failed to quantify specialty-concordant SE. SE was often omitted, not quantified, and/or lacked a timeline in treatment consultations in our sample. Physicians should articulate, quantify, and assign a timeline for SE to optimize SDM.

Sections du résumé

BACKGROUND BACKGROUND
Effective communication of treatment side effects (SE) is critical for shared decision-making (SDM) in localized prostate cancer. We sought to qualitatively characterize how physicians communicate SE in consultations.
METHODS METHODS
We transcribed 50 initial prostate cancer treatment consultations across nine multidisciplinary providers (Urologists, Radiation Oncologists, Medical Oncologists) at our tertiary referral, academic center. Coders identified quotes describing SE and used an inductive approach to establish a hierarchy for granularity of communication: (1) not mentioned, (2) name only, (3) generalization("high"), (4) average incidence without timepoint, (5) average incidence with timepoint, and (6) precision estimate. We reported the most granular mode of communication for each SE throughout the consultation overall and across specialty and tumor risk.
RESULTS RESULTS
Among consultations discussing surgery (n = 40), erectile dysfunction (ED) and urinary incontinence (UI) were omitted in 15% and 12%, not quantified (name only or generalization) in 47% and 30%, and noted as average incidence without timeline in 8% and 8%, respectively. In only 30% and 49% were ED and UI quantified with timeline (average incidence with timeline or precision estimate), respectively. Among consultations discussing radiation (n = 36), irritative urinary symptoms, ED, and other post-radiotherapy SE were omitted in 22%, 42%, and 64-67%, not quantified in 61%, 33%, and 23-28%, and noted as average incidence without timeline in 8%, 22%, and 6-8%, respectively. In only 3-8% were post-radiotherapy SE quantified with timeline. Specialty concordance (but not tumor risk) was associated with higher granularity of communication, though physicians frequently failed to quantify specialty-concordant SE.
CONCLUSIONS CONCLUSIONS
SE was often omitted, not quantified, and/or lacked a timeline in treatment consultations in our sample. Physicians should articulate, quantify, and assign a timeline for SE to optimize SDM.

Identifiants

pubmed: 38396054
doi: 10.1038/s41391-024-00806-2
pii: 10.1038/s41391-024-00806-2
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NCI NIH HHS
ID : K08 CA230155
Pays : United States

Informations de copyright

© 2024. The Author(s).

Références

Eastham JA, Auffenberg GB, Barocas DA, Chou R, Crispino T, Davis JW, et al. Clinically localized prostate cancer: AUA/ASTRO guideline, Part I: Introduction, risk assessment, staging, and risk-based management. J Urol. 2022;208:10–8. https://doi.org/10.1097/JU.0000000000002757 .
doi: 10.1097/JU.0000000000002757 pubmed: 35536144
Hoffmann TC, Montori VM, Del Mar C. The connection between evidence-based medicine and shared decision-making. JAMA. 2014;312:1295–6. https://doi.org/10.1001/jama.2014.10186 .
doi: 10.1001/jama.2014.10186 pubmed: 25268434
Montori VM, Brito JP, Murad MH. The optimal practice of evidence-based medicine: incorporating patient preferences in practice guidelines. JAMA. 2013;310:2503–4. https://doi.org/10.1001/jama.2013.281422 .
doi: 10.1001/jama.2013.281422 pubmed: 24165826
Litwin MS, Tan HJ. The diagnosis and treatment of prostate cancer: a review. JAMA. 2017;317:2532–42. https://doi.org/10.1001/jama.2017.7248 .
doi: 10.1001/jama.2017.7248 pubmed: 28655021
Wang DS, Jani AB, Sesay M, Tai CG, Lee DK, Echt KV, et al. Video-based educational tool improves patient comprehension of common prostate health terminology. Cancer. 2015;121:733–40. https://doi.org/10.1002/cncr.29101 .
doi: 10.1002/cncr.29101 pubmed: 25393416
Daskivich TJ, Gale R, Luu M, Naser-Tavakolian A, Venkataramana A, Khodyakov D, et al. Variation in communication of competing risks of mortality in prostate cancer treatment consultations. J Urol. 2022. https://doi.org/10.1097/JU.0000000000002675 .
Daskivich TJ, Gale R, Luu M, Khodyakov D, Anger JT, Freedland SJ, et al. Patient preferences for communication of life expectancy in prostate cancer treatment consultations. JAMA Surg. 2021. https://doi.org/10.1001/jamasurg.2021.5803 .
doi: 10.1001/jamasurg.2021.5803 pmcid: 8581791
Hope ACA. A simplified Monte Carlo significance test procedure. J R Stat Soc. 1968;30:582–298.
Gilbert SM, Sanda MG, Dunn RL, Greenfield TK, Hembroff L, Klein E, et al. Satisfaction with information used to choose prostate cancer treatment. J Urol. 2014;191:1265–71. https://doi.org/10.1016/j.juro.2013.12.008 .
doi: 10.1016/j.juro.2013.12.008 pubmed: 24333514
Daskivich TJ, van de Poll-Franse LV, Kwan L, Sadetsky N, Stein DM, Litwin MS. From bad to worse: comorbidity severity and quality of life after treatment for early-stage prostate cancer. Prostate Cancer Prostatic Dis. 2010;13:320–7. https://doi.org/10.1038/pcan.2010.33 .
doi: 10.1038/pcan.2010.33 pubmed: 20838413
Barocas DA, Alvarez J, Resnick MJ, Koyama T, Hoffman KE, Tyson MD, et al. Association between radiation therapy, surgery, or observation for localized prostate cancer and patient-reported outcomes after 3 years. JAMA. 2017;317:1126–40. https://doi.org/10.1001/jama.2017.1704 .
doi: 10.1001/jama.2017.1704 pubmed: 28324093 pmcid: 5782813
Morgan SC, Hoffman K, Loblaw DA, Buyyounouski MK, Patton C, Barocas D, et al. Hypofractionated radiation therapy for localized prostate cancer: an ASTRO, ASCO, and AUA evidence-based guideline. J Clin Oncol. 2018:JCO1801097. https://doi.org/10.1200/JCO.18.01097 .
Hu JC, Gold KF, Pashos CL, Mehta SS, Litwin MS. Role of surgeon volume in radical prostatectomy outcomes. J Clin Oncol. 2003;21:401–5.
doi: 10.1200/JCO.2003.05.169 pubmed: 12560426
Ross RW, Kantoff PW. Predicting outcomes in prostate cancer: how many more nomograms do we need? J Clin Oncol. 2007;25:3563–4. https://doi.org/10.1200/JCO.2007.12.2721 .
doi: 10.1200/JCO.2007.12.2721 pubmed: 17704399
Tan HJ, Zhou X, Spratte BN, McMahon S, Nielsen ME, Lund J, et al. Patient reported vs claims based measures of health for modeling life expectancy in men with prostate cancer. J Urol. 2021;205:434–40. https://doi.org/10.1097/JU.0000000000001355 .
doi: 10.1097/JU.0000000000001355 pubmed: 32909877
Barocas DA, Chen V, Cooperberg M, Goodman M, Graff JJ, Greenfield S, et al. Using a population-based observational cohort study to address difficult comparative effectiveness research questions: the CEASAR study. J Comp Eff Res. 2013;2:445–60. https://doi.org/10.2217/cer.13.34 .
doi: 10.2217/cer.13.34 pubmed: 24236685
Resnick MJ, Koyama T, Fan KH, Albertsen PC, Goodman M, Hamilton AS, et al. Long-term functional outcomes after treatment for localized prostate cancer. N Engl J Med. 2013;368:436–45. https://doi.org/10.1056/NEJMoa1209978 .
doi: 10.1056/NEJMoa1209978 pubmed: 23363497 pmcid: 3742365
Sanda MG, Dunn RL, Michalski J, Sandler HM, Northouse L, Hembroff L, et al. Quality of life and satisfaction with outcome among prostate-cancer survivors. N Engl J Med. 2008;358:1250–61. https://doi.org/10.1056/NEJMoa074311 .
doi: 10.1056/NEJMoa074311 pubmed: 18354103
Stanford JL, Feng Z, Hamilton AS, Gilliland FD, Stephenson RA, Eley JW, et al. Urinary and sexual function after radical prostatectomy for clinically localized prostate cancer: the prostate cancer outcomes study. JAMA. 2000;283:354–60. https://doi.org/10.1001/jama.283.3.354 .
doi: 10.1001/jama.283.3.354 pubmed: 10647798
Potosky AL, Davis WW, Hoffman RM, Stanford JL, Stephenson RA, Penson DF, et al. Five-year outcomes after prostatectomy or radiotherapy for prostate cancer: the prostate cancer outcomes study. J Natl Cancer Inst. 2004;96:1358–67. https://doi.org/10.1093/jnci/djh259 .
doi: 10.1093/jnci/djh259 pubmed: 15367568
Bagshaw HP, Arnow KD, Trickey AW, Leppert JT, Wren SM, Morris AM. Assessment of second primary cancer risk among men receiving primary radiotherapy vs surgery for the treatment of prostate cancer. JAMA Netw Open. 2022;5:e2223025 https://doi.org/10.1001/jamanetworkopen.2022.23025 .
doi: 10.1001/jamanetworkopen.2022.23025 pubmed: 35900763 pmcid: 9335142
Hamilton AS, Stanford JL, Gilliland FD, Albertsen PC, Stephenson RA, Hoffman RM, et al. Health outcomes after external-beam radiation therapy for clinically localized prostate cancer: results from the prostate cancer outcomes study. J Clin Oncol. 2001;19:2517–26. https://doi.org/10.1200/JCO.2001.19.9.2517 .
doi: 10.1200/JCO.2001.19.9.2517 pubmed: 11331331

Auteurs

Timothy J Daskivich (TJ)

Department of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA. Timothy.Daskivich@csmc.edu.
Cedars-Sinai Center for Outcomes Research and Education (CS-CORE), Cedars-Sinai Medical Center, Los Angeles, CA, USA. Timothy.Daskivich@csmc.edu.

Aurash Naser-Tavakolian (A)

Department of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Rebecca Gale (R)

Cedars-Sinai Center for Outcomes Research and Education (CS-CORE), Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Michael Luu (M)

Department of Biostatistics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Nadine Friedrich (N)

Department of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Abhi Venkataramana (A)

Institute of Urology, University of Southern California, Los Angeles, CA, USA.

Dmitry Khodyakov (D)

RAND Institute, Santa Monica, CA, USA.

Edwin Posadas (E)

Department of Medicine, Division of Medical Oncology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Howard Sandler (H)

Department of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Brennan Spiegel (B)

Cedars-Sinai Center for Outcomes Research and Education (CS-CORE), Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Department of Medicine, Divisions of Gastroenterology and Health Services Research, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Stephen J Freedland (SJ)

Department of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Section of Urology, Durham VA Medical Center, Durham, NC, USA.

Classifications MeSH