Validation of Endogenous Control Genes by Real-Time Quantitative Reverse Transcriptase Polymerase Chain Reaction for Acute Leukemia Gene Expression Studies.

RT-qPCR gene expression leukemia reference genes

Journal

Genes
ISSN: 2073-4425
Titre abrégé: Genes (Basel)
Pays: Switzerland
ID NLM: 101551097

Informations de publication

Date de publication:
24 Jan 2024
Historique:
received: 07 12 2023
revised: 09 01 2024
accepted: 22 01 2024
medline: 24 2 2024
pubmed: 24 2 2024
entrez: 24 2 2024
Statut: epublish

Résumé

Reference genes are used as internal reaction controls for gene expression analysis, and for this reason, they are considered reliable and must meet several important criteria. In view of the absence of studies regarding the best reference gene for the analysis of acute leukemia patients, a panel of genes commonly used as endogenous controls was selected from the literature for stability analysis: Glyceraldehyde-3-phosphate dehydrogenase (

Identifiants

pubmed: 38397141
pii: genes15020151
doi: 10.3390/genes15020151
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico
ID : PPSUS

Auteurs

Flávia Melo Cunha de Pinho Pessoa (FMCP)

Department of Medicine, Pharmacogenetics Laboratory, Drug Research and Development Center (NPDM), Federal University of Ceará, Fortaleza 60430-275, CE, Brazil.

Vitória Beatriz de Jesus Viana (VBJ)

Department of Biological Sciences, Oncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.

Marcelo Braga de Oliveira (MB)

Department of Biological Sciences, Oncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.

Beatriz Maria Dias Nogueira (BMD)

Department of Medicine, Pharmacogenetics Laboratory, Drug Research and Development Center (NPDM), Federal University of Ceará, Fortaleza 60430-275, CE, Brazil.

Rodrigo Monteiro Ribeiro (RM)

Department of Hematology, Fortaleza General Hospital (HGF), Fortaleza 60150-160, CE, Brazil.

Deivide de Sousa Oliveira (DS)

Department of Medicine, Pharmacogenetics Laboratory, Drug Research and Development Center (NPDM), Federal University of Ceará, Fortaleza 60430-275, CE, Brazil.
Department of Hematology, Fortaleza General Hospital (HGF), Fortaleza 60150-160, CE, Brazil.

Germison Silva Lopes (GS)

Department of Hematology, César Cals General Hospital, Fortaleza 60015-152, CE, Brazil.

Ricardo Parente Garcia Vieira (RPG)

Department of Hematology, São Vicente de Paulo Maternity Hospital, Barbalha 63180-000, CE, Brazil.

Manoel Odorico de Moraes Filho (MO)

Department of Medicine, Pharmacogenetics Laboratory, Drug Research and Development Center (NPDM), Federal University of Ceará, Fortaleza 60430-275, CE, Brazil.

Maria Elisabete Amaral de Moraes (MEA)

Department of Medicine, Pharmacogenetics Laboratory, Drug Research and Development Center (NPDM), Federal University of Ceará, Fortaleza 60430-275, CE, Brazil.

André Salim Khayat (AS)

Department of Biological Sciences, Oncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.

Fabiano Cordeiro Moreira (FC)

Department of Biological Sciences, Oncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.

Caroline Aquino Moreira-Nunes (CA)

Department of Medicine, Pharmacogenetics Laboratory, Drug Research and Development Center (NPDM), Federal University of Ceará, Fortaleza 60430-275, CE, Brazil.
Department of Biological Sciences, Oncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.
Central Unity, Molecular Biology Laboratory, Clementino Fraga Group, Fortaleza 60115-170, CE, Brazil.

Classifications MeSH