Biofilm and How It Relates to Prosthetic Joint Infection.

Antimicrobial peptide Bacteriophage Biofilm Prosthetic joint infection Total joint arthroplasty

Journal

The Orthopedic clinics of North America
ISSN: 1558-1373
Titre abrégé: Orthop Clin North Am
Pays: United States
ID NLM: 0254463

Informations de publication

Date de publication:
Apr 2024
Historique:
medline: 26 2 2024
pubmed: 26 2 2024
entrez: 25 2 2024
Statut: ppublish

Résumé

Prosthetic joint infection following total joint arthroplasty is a devastating complication, resulting in increased morbidity and mortality for the patient. The formation of a biofilm on implanted hardware contributes to the difficulty in successful identification and eradication of the infection. Antibiotic therapy and surgical intervention are necessary for addressing this condition; we present a discussion on different treatment options, including those that are not yet routinely utilized in the clinical setting or are under investigation, to highlight the present and future of PJI management.

Identifiants

pubmed: 38403363
pii: S0030-5898(23)00189-X
doi: 10.1016/j.ocl.2023.10.001
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

161-169

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure The authors have nothing to disclose.

Auteurs

Ashley E MacConnell (AE)

Department of Orthopaedic Surgery and Rehabilitation, Loyola University Medical Center, 2160 South First Avenue, Suite 1700, Maywood, IL 60153, USA. Electronic address: ashley.macconnell@luhs.org.

Ashley E Levack (AE)

Department of Orthopaedic Surgery and Rehabilitation, Loyola University Medical Center, 2160 South First Avenue, Suite 1700, Maywood, IL 60153, USA.

Nicholas M Brown (NM)

Department of Orthopaedic Surgery and Rehabilitation, Loyola University Medical Center, 2160 South First Avenue, Suite 1700, Maywood, IL 60153, USA.

Classifications MeSH