Development of a solid-supported light-triggered nitric oxide donor.
cellular delivery
nitric oxide
photocleavable donors
solid-phase chemistry
Journal
Journal of photochemistry and photobiology. A, Chemistry
ISSN: 1010-6030
Titre abrégé: J Photochem Photobiol A Chem
Pays: Switzerland
ID NLM: 9883240
Informations de publication
Date de publication:
01 May 2024
01 May 2024
Historique:
pmc-release:
01
05
2025
medline:
26
2
2024
pubmed:
26
2
2024
entrez:
26
2
2024
Statut:
ppublish
Résumé
Nitric Oxide (NO) photocleavable donors are useful tools for interrogating nitric oxide signalling and have potential use in photopharmacological applications. There is currently intensive research into newer methods to improve NO release and kinetic profiles. Herein, we report the design and synthesis of a solid-supported photocleavable NO donor synthesized by ligating an
Identifiants
pubmed: 38405370
doi: 10.1016/j.jphotochem.2024.115466
pmc: PMC10883461
pii:
doi:
Types de publication
Journal Article
Langues
eng
Déclaration de conflit d'intérêts
5.Conflicts of interest A.R.L. declares a financial stake in BioLum Sciences, LLC. This work was funded as a subaward of the NIH grant 1R41GM140575-01 awarded to BioLum Sciences, LLC.