UNC-30/PITX coordinates neurotransmitter identity with postsynaptic GABA receptor clustering.
Journal
bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187
Informations de publication
Date de publication:
14 Feb 2024
14 Feb 2024
Historique:
medline:
26
2
2024
pubmed:
26
2
2024
entrez:
26
2
2024
Statut:
epublish
Résumé
Terminal selectors are transcription factors that control neuronal identity by regulating the expression of key effector molecules, such as neurotransmitter (NT) biosynthesis proteins, ion channels and neuropeptides. Whether and how terminal selectors control neuronal connectivity is poorly understood. Here, we report that UNC-30 (PITX2/3), the terminal selector of GABA motor neuron identity in
Identifiants
pubmed: 38405977
doi: 10.1101/2024.02.14.580278
pmc: PMC10888783
pii:
doi:
Types de publication
Preprint
Langues
eng