UNC-30/PITX coordinates neurotransmitter identity with postsynaptic GABA receptor clustering.


Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
14 Feb 2024
Historique:
medline: 26 2 2024
pubmed: 26 2 2024
entrez: 26 2 2024
Statut: epublish

Résumé

Terminal selectors are transcription factors that control neuronal identity by regulating the expression of key effector molecules, such as neurotransmitter (NT) biosynthesis proteins, ion channels and neuropeptides. Whether and how terminal selectors control neuronal connectivity is poorly understood. Here, we report that UNC-30 (PITX2/3), the terminal selector of GABA motor neuron identity in

Identifiants

pubmed: 38405977
doi: 10.1101/2024.02.14.580278
pmc: PMC10888783
pii:
doi:

Types de publication

Preprint

Langues

eng

Auteurs

Classifications MeSH