Effects of periodic breathing on sleep at high altitude: a randomized, placebo-controlled, crossover study using inspiratory CO

Cheyne-Stokes acclimatization carbon dioxide hypobaric hypoxia placebo polysomnography

Journal

The Journal of physiology
ISSN: 1469-7793
Titre abrégé: J Physiol
Pays: England
ID NLM: 0266262

Informations de publication

Date de publication:
26 Feb 2024
Historique:
received: 23 08 2023
accepted: 17 01 2024
medline: 26 2 2024
pubmed: 26 2 2024
entrez: 26 2 2024
Statut: aheadofprint

Résumé

Hypoxia at high altitude facilitates changes in ventilatory control that can lead to nocturnal periodic breathing (nPB). Here, we introduce a placebo-controlled approach to prevent nPB by increasing inspiratory CO

Identifiants

pubmed: 38408065
doi: 10.1113/JP285397
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Austrian Science Fund FWF
ID : I 4891
Pays : Austria

Informations de copyright

© 2024 The Authors. The Journal of Physiology published by John Wiley & Sons Ltd on behalf of The Physiological Society.

Références

Ainslie, P. N., Lucas, S. J. E., & Burgess, K. R. (2013). Breathing and sleep at high altitude. Respiratory Physiology & Neurobiology, 188(3), 233-256.
Berry, R. B. Q. S., & Abreu, A. R., for the American Academy of Sleep Medicine (2020). The AASM manual for the scoring of sleep and associated events: Rules, terminology and technical specifications. American Academy of Sleep Medicine.
Berssenbrugge, A., Dempsey, J., Iber, C., Skatrud, J., & Wilson, P. (1983). Mechanisms of hypoxia-induced periodic breathing during sleep in humans. The Journal of Physiology, 343(1), 507-526.
Bird, J. D., Kalker, A., Rimke, A. N., Chan, J. S., Chan, G., Saran, G., Jendzjowsky, N. G., Wilson, R. J. A., Brutsaert, T. D., Sherpa, M. T., & Day, T. A. (2021). Severity of central sleep apnea does not affect sleeping oxygen saturation during ascent to high altitude. Journal of Applied Physiology, 131(5), 1432-1443.
Bloch, K. E., Buenzli, J. C., Latshang, T. D., & Ulrich, S. (2015). Sleep at high altitude: Guesses and facts. Journal of Applied Physiology, 119(12), 1466-1480.
Boulos, M. I., Jairam, T., Kendzerska, T., Im, J., Mekhael, A., & Murray, B. J. (2019). Normal polysomnography parameters in healthy adults: A systematic review and meta-analysis. Lancet Respiratory Medicine, 7(6), 533-543.
Burgess, K. R., Johnson, P. L., & Edwards, N. (2004). Central and obstructive sleep apnoea during ascent to high altitude. Respirology, 9(2), 222-229.
Burgess, K. R., Lucas, S. J. E., Burgess, K. M. E., Sprecher, K. E., Donnelly, J., Basnet, A. S., Tymko, M. M., Day, T., Smith, K., Lewis, N., & Ainslie, P. N. (2018). Increasing cerebral blood flow reduces the severity of central sleep apnea at high altitude. Journal of Applied Physiology, 124(5), 1341-1348.
Burgess, K. R., Lucas, S. J. E., Shepherd, K., Dawson, A., Swart, M., Thomas, K. N., Lucas, R. A. I., Donnelly, J., Peebles, K. C., Basnyat, R., & Ainslie, P. N. (2013). Worsening of central sleep apnea at high altitude-a role for cerebrovascular function. Journal of Applied Physiology, 114(8), 1021-1028.
Byun, J.-H.o, Kim, K. T., Moon, H.-J., Motamedi, G. K., & Cho, Y. W. (2019). The first night effect during polysomnography, and patients' estimates of sleep quality. Psychiatry Research, 274, 27-29.
Chuang, I.-C., Dong, H.-P., Yang, R.-C., Wang, T.-H., Tsai, J.-H., Yang, P.-H., & Huang, M.-S. (2010). Effect of carbon dioxide on pulmonary vascular tone at various pulmona ry arterial pressure levels induced by endothelin-1. Lung, 188(3), 199-207.
Conkin, J. (2016). Equivalent Air Altitude and the Alveolar Gas Equation. Aerospace Medicine and Human Performance, 87(1), 61-64.
Dempsey, J. A. (2005). Crossing the apnoeic threshold: Causes and consequences. Experimental Physiology, 90(1), 13-24.
Efron, B., & Narasimhan, B. (2020). The automatic construction of bootstrap confidence intervals. Journal of Computational and Graphical Statistics, 29(3), 608-619.
Goldenberg, F., Richalet, J. P., Jouhandin, M., Gisquet, A., Keromes, A., & Larmignat, P. (1988). [Periodic respiration during sleep at high altitude. Effects of a hypnotic benzodiazepine, loprazolam]. La Presse Medicale, 17, 471-474.
Graf, L. C., Furian, M., Bitos, K., Mademilov, M., Abdraeva, A., Buenzli, J., Buenzli, S., Aidaralieva, S., Sheraliev, U., Mayer, L. C., Schneider, S. R., Sooronbaev, T. M., Ulrich, S., & Bloch, K. E. (2022). Effect of altitude and acetazolamide on sleep and nocturnal breathing in healthy lowlanders 40y of age or older. Data from a randomized trial. Sleep, 46(4), zsac269.
Henke, K. G., Dempsey, J. A., Badr, M. S., Kowitz, J. M., & Skatrud, J. B. (1991). Effect of sleep-induced increases in upper airway resistance on respiratory muscle activity. Journal of Applied Physiology, 70(1), 158-168.
Javaheri, S., & Dempsey, J. A. (2013). Central sleep apnea. Comprehensive Physiology, 3, 141-163.
Joern, A. T. (1970). Short-term changes in sleep patterns on arrival at the South Polar Plateau. Archives of Internal Medicine, 125(4), 649-654.
Johnson, P. L., Edwards, N., Burgess, K. R., & Sullivan, C. E. (2010). Sleep architecture changes during a trek from 1400 to 5000 m in the Nepal Himalaya. Journal of Sleep Research, 19(1p2), 148-156.
Khoo, M. C. K., Anholm, J. D., Ko, S.-W., Downey, R., Powles, A. C. P., Sutton, J. R., & Houston, C. S. (1996). Dynamics of periodic breathing and arousal during sleep at extreme altitude. Respiration Physiology, 103(1), 33-43.
Küpper, T., Schöffl, V., & Netzer, N. (2008). Cheyne Stokes breathing at high altitude: A helpful response or a troublemaker? Sleep and Breathing, 12(2), 123-127.
Lahiri, S., Maret, K., & Sherpa, M. G. (1983). Dependence of high altitude sleep apnea on ventilatory sensitivity to hypoxia. Respiration Physiology, 52(3), 281-301.
Lanfranchi, P. A., Braghiroli, A., Bosimini, E., Mazzuero, G., Colombo, R., Donner, C. F., & Giannuzzi, P. (1999). Prognostic value of nocturnal Cheyne-Stokes respiration in chronic heart failure. Circulation, 99(11), 1435-1440.
Langford, N. J. (2005). Carbon dioxide poisoning. Toxicological Reviews, 24(4), 229-235.
Latshang, T. D., Lo Cascio, C. M., Stöwhas, A.-C., Grimm, M., Stadelmann, K., Tesler, N., Achermann, P., Huber, R., Kohler, M., & Bloch, K. E. (2013). Are nocturnal breathing, sleep, and cognitive performance impaired at moderate altitude (1,630-2,590 m)? Sleep, 36(12), 1969-1976.
Latshang, T. D., Tardent, R. P. M., Furian, M., Flueck, D., Segitz, S. D., Mueller-Mottet, S., Kohler, M., Ulrich, S., & Bloch, K. E. (2019). Sleep and breathing disturbances in patients with chronic obstructive pulmonary disease traveling to altitude: A randomized trial. Sleep, 42(1), zsy203.
Liu, H.-M., Chiang, I.-J., Kuo, K. N., Liou, C.-M., & Chen, C. (2017). The effect of acetazolamide on sleep apnea at high altitude: A systematic review and meta-analysis. Therapeutic Advances in Respiratory Disease, 11(1), 20-29.
Lombardi, C., Meriggi, P., Agostoni, P., Faini, A., Bilo, G., Revera, M., Caldara, G., Di Rienzo, M., Castiglioni, P., Maurizio, B., Gregorini, F., Mancia, G., Parati, G., & HIGHCARE Investigators. (2013). High-altitude hypoxia and periodic breathing during sleep: Gender-related differences. Journal of Sleep Research, 22(3), 322-330.
Lovering, A. T., Fraigne, J. J., Witali L, D.-B., Vidruk, E. H., & Orem, J. M. (2003). Hypocapnia decreases the amount of rapid eye movement sleep in cats. Sleep, 26(8), 961-967.
Mcsharry, D. G., Saboisky, J. P., Deyoung, P., Matteis, P., Jordan, A. S., Trinder, J., Smales, E., Hess, L., Guo, M., & Malhotra, A. (2013). A mechanism for upper airway stability during slow wave sleep. Sleep, 36(4), 555-563.
Mizuno, K., Asano, K., & Okudaira, N. (1993). Sleep and respiration under acute hypobaric hypoxia. Japanese Journal of Physiology, 43(2), 161-175.
Natani, K. (1970). Long-term changes in sleep patterns in men on the South Polar Plateau. Archives of Internal Medicine, 125(4), 655-659.
Nicholson, A. N., Smith, P. A., Stone, B. M., Bradwell, A. R., & Coote, J. H. (1988). Altitude insomnia: Studies during an expedition to the Himalayas. Sleep, 11(4), 354-361.
Nussbaumer-Ochsner, Y., Latshang, T. D., Ulrich, S., Kohler, M., Thurnheer, R., & Bloch, K. E. (2012). Patients with obstructive sleep apnea syndrome benefit from acetazolamide during an altitude sojourn: A randomized, placebo-controlled, double-blind trial. Chest, 141(1), 131-138.
Nussbaumer-Ochsner, Y., Schuepfer, N., Ulrich, S., & Bloch, K. E. (2010). Exacerbation of sleep apnoea by frequent central events in patients with the obstructive sleep apnoea syndrome at altitude: A randomised trial. Thorax, 65(5), 429-435.
Nussbaumer-Ochsner, Y., Ursprung, J., Siebenmann, C., Maggiorini, M., & Bloch, K. E. (2012). Effect of short-term acclimatization to high altitude on sleep and nocturnal breathing. Sleep, 35(3), 419-423.
Panjwani, U., Thakur, L., Anand, J. P., & Banerjee, P. K. (2007). Sleep architecture at 3500 meters in a sample of Indians. Sleep and Biological Rhythms, 5(3), 159-165.
Patz, D. S., Patz, M. D., & Hackett, P. H. (2013). Dead space mask eliminates central apnea at altitude. High Altitude Medicine & Biology, 14(2), 168-174.
Ritschel, W. A., Paulos, C., Arancibia, A., Agrawal, M. A., Wetzelsberger, K. M., & Lücker, P. W. (1998). Pharmacokinetics of acetazolamide in healthy volunteers after short- and long-term exposure to high altitude. Journal of Clinical Pharmacology, 38(6), 533-539.
Salvaggio, A., Insalaco, G., Marrone, O., Romano, S., Braghiroli, A., Lanfranchi, P., Patruno, V., Donner, C.f, & Bonsignore, G. (1998). Effects of high-altitude periodic breathing on sleep and arterial oxyhaemoglobin saturation. European Respiratory Journal, 12(2), 408-413.
Shogilev, D. J., Tanner, J. B., Chang, Y., & Harris, N. S. (2015). Periodic Breathing and Behavioral Awakenings at High Altitude. Sleep Disorder, 2015, 1.
Stefani, A., Heidbreder, A., Hackner, H., & Högl, B. (2017). Validation of a leg movements count and periodic leg movements analysis in a custom polysomnography system. Biomedicine Central Neurology, 17(1), 42.
Tan, L.u, Latshang, T. D., Aeschbacher, S. S., Huber, F., Flueck, D., Lichtblau, M., Ulrich, S., Hasler, E. D., Scheiwiller, P. M., Ulrich, S., Bloch, K. E., & Furian, M. (2020). Effect of nocturnal oxygen therapy on nocturnal hypoxemia and sleep apnea among patients with chronic obstructive pulmonary disease traveling to 2048 meters: A randomized clinical trial. Journal of the American Medical Association Network Open, 3(6), e207940.
Waggener, T. B., Brusil, P. J., Kronauer, R. E., Gabel, R. A., & Inbar, G. F. (1984). Strength and cycle time of high-altitude ventilatory patterns in unacclimatized humans. Journal of Applied Physiology Respiratory, Environmental and Exercise Physiology, 56, 576-581.
Weil, J. V. (1985). Sleep at high-altitude. Clinics in Chest Medicine, 6(4), 615-621.
Xi, L., Smith, C. A., Saupe, K. W., Henderson, K. S., & Dempsey, J. A. (1993). Effects of rapid-eye-movement sleep on the apneic threshold in dogs. Journal of Applied Physiology, 75(3), 1129-1139.
Zieliński, J., Koziej, M., Mańkowski, M., Sarybaev, A. S., Tursalieva, J. S., Sabirov, I. S., Karamuratov, A. S., & Mirrakhimov, M. M. (2000). The quality of sleep and periodic breathing in healthy subjects at an altitude of 3,200 m. High Altitude Medicine & Biology, 1(4), 331-336.

Auteurs

Abubaker Ibrahim (A)

Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

Ambra Stefani (A)

Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

Matteo Cesari (M)

Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

Johanna Roche (J)

Institute of Mountain Emergency Medicine, Eurac Research, Bolzano, Italy.

Hannes Gatterer (H)

Institute of Mountain Emergency Medicine, Eurac Research, Bolzano, Italy.

Evi Holzknecht (E)

Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

Rachel Turner (R)

Institute of Mountain Emergency Medicine, Eurac Research, Bolzano, Italy.

Giovanni Vinetti (G)

Institute of Mountain Emergency Medicine, Eurac Research, Bolzano, Italy.

Michael Furian (M)

Department of Respiratory Medicine, University Hospital of Zurich, Zurich, Switzerland.

Anna Heidbreder (A)

Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

Birgit Högl (B)

Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

Christoph Siebenmann (C)

Institute of Mountain Emergency Medicine, Eurac Research, Bolzano, Italy.

Classifications MeSH