Carotid Near-Occlusion: Surgical or Conservative Management? Retrospective Multicenter Study.


Journal

Annals of vascular surgery
ISSN: 1615-5947
Titre abrégé: Ann Vasc Surg
Pays: Netherlands
ID NLM: 8703941

Informations de publication

Date de publication:
02 Feb 2024
Historique:
received: 04 10 2023
revised: 14 11 2023
accepted: 26 11 2023
medline: 26 2 2024
pubmed: 26 2 2024
entrez: 26 2 2024
Statut: aheadofprint

Résumé

Carotid near-occlusion (CNO) represents an anatomical-functional condition characterized by severe (more than 90%) internal carotid artery stenosis which can lead to a distal lumen diameter greater or less than 2 mm. CNO can be divided into a less severe subgroup (without lumen full collapse: diameter >2 mm) and a more severe subgroup (with lumen full collapse: diameter <2 mm). The decision for revascularization is still highly debated in Literature. The aim of the present multicenter retrospective study is to analyze the incidence of perioperative (30 days) and follow-up complications in 2 groups of patients with or without distal internal carotid lumen full collapse. Between January 2011 and March 2023, in 5 Vascular Surgery Units, 67 patients (49 male, 73% and 18 females, 27%) with CNO underwent carotid endarterectomy: 28 (41.7%) with lumen diameter <2 mm and 39 (58.3%) with diameter >2 mm. 19 patients were symptomatic and 48 asymptomatic. The outcomes considered for comparative analysis were: perioperative neurological and cardiac complications, carotid restenosis or occlusion at follow-up. Both groups were homogeneous in terms of risk factors, morphological features and pharmacological treatments. In the group with lumen <2 mm, 3 perioperative major events (10.7%) occurred (1 ischemic stroke, 1 hemorrhagic stroke, 1 myocardial infarction) and 2 (7.1%) at follow-up (average 11 ± 14.5 months; 1 asymptomatic carotid occlusion, 1 hemodynamic restenosis treated with stenting). No event was recorded in the group with lumen >2 mm. According to our results CNO patients show different complication risk according to the presence or not of distal lumen collapse. The later seems to play a significant role in perioperative and follow-up complication rate. These results therefore support a surgical treatment only in patients with CNO without lumen full collapse.

Sections du résumé

BACKGROUND BACKGROUND
Carotid near-occlusion (CNO) represents an anatomical-functional condition characterized by severe (more than 90%) internal carotid artery stenosis which can lead to a distal lumen diameter greater or less than 2 mm. CNO can be divided into a less severe subgroup (without lumen full collapse: diameter >2 mm) and a more severe subgroup (with lumen full collapse: diameter <2 mm). The decision for revascularization is still highly debated in Literature. The aim of the present multicenter retrospective study is to analyze the incidence of perioperative (30 days) and follow-up complications in 2 groups of patients with or without distal internal carotid lumen full collapse.
METHODS METHODS
Between January 2011 and March 2023, in 5 Vascular Surgery Units, 67 patients (49 male, 73% and 18 females, 27%) with CNO underwent carotid endarterectomy: 28 (41.7%) with lumen diameter <2 mm and 39 (58.3%) with diameter >2 mm. 19 patients were symptomatic and 48 asymptomatic. The outcomes considered for comparative analysis were: perioperative neurological and cardiac complications, carotid restenosis or occlusion at follow-up. Both groups were homogeneous in terms of risk factors, morphological features and pharmacological treatments.
RESULTS RESULTS
In the group with lumen <2 mm, 3 perioperative major events (10.7%) occurred (1 ischemic stroke, 1 hemorrhagic stroke, 1 myocardial infarction) and 2 (7.1%) at follow-up (average 11 ± 14.5 months; 1 asymptomatic carotid occlusion, 1 hemodynamic restenosis treated with stenting). No event was recorded in the group with lumen >2 mm.
CONCLUSIONS CONCLUSIONS
According to our results CNO patients show different complication risk according to the presence or not of distal lumen collapse. The later seems to play a significant role in perioperative and follow-up complication rate. These results therefore support a surgical treatment only in patients with CNO without lumen full collapse.

Identifiants

pubmed: 38408393
pii: S0890-5096(24)00031-1
doi: 10.1016/j.avsg.2023.11.047
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

133-139

Informations de copyright

Copyright © 2024 Elsevier Inc. All rights reserved.

Auteurs

Gabriele Pagliariccio (G)

Vascular Surgery Department, ASL Teramo, Teramo, Italy. Electronic address: gabriele.pagliariccio@gmail.com.

Ilenia Di Sario (I)

Vascular Surgery Department, ASL Teramo, Teramo, Italy.

Laura Capoccia (L)

Vascular Surgery Department, Avezzano Hospital, Avezzano, Italy.

Marcello D'Elia (M)

Vascular Surgery Department, Avezzano Hospital, Avezzano, Italy.

Gennaro Bafile (G)

Vascular Surgery Department, L'Aquila Hospital, L'Aquila, Italy.

Marco Leopardi (M)

Vascular Surgery Department, L'Aquila Hospital, L'Aquila, Italy.

Franco Fiore (F)

Vascular Surgery Department, Chieti Hospital, Chieti, Italy.

Armando Palmieri (A)

Vascular Surgery Department, Chieti Hospital, Chieti, Italy.

Lorenzo Antico (L)

Vascular Surgery Department, Pescara Hospital, Pescara, Italy.

Antonio Antico (A)

Vascular Surgery Department, Pescara Hospital, Pescara, Italy.

Classifications MeSH