Implementation of a Multidimensional Strategy to Reduce Post-PCI Bleeding Risk.

evidence based practice healthcare delivery hospitals percutaneous coronary intervention quality improvement

Journal

Circulation. Cardiovascular interventions
ISSN: 1941-7632
Titre abrégé: Circ Cardiovasc Interv
Pays: United States
ID NLM: 101499602

Informations de publication

Date de publication:
Mar 2024
Historique:
pubmed: 27 2 2024
medline: 27 2 2024
entrez: 27 2 2024
Statut: ppublish

Résumé

The American College of Cardiology Reduce the Risk: PCI Bleed Campaign was a hospital-based quality improvement campaign designed to reduce post-percutaneous coronary intervention (PCI) bleeding events. The aim of the campaign was to provide actionable evidence-based tools for participants to review, adapt, and adopt, depending upon hospital resources and engagement. We used data from 8 757 737 procedures in the National Cardiovascular Data Registry between 2015 and 2021 to compare patient and hospital characteristics and bleeding outcomes among campaign participants (n=195 hospitals) and noncampaign participants (n=1384). Post-PCI bleeding risk was compared before and after campaign participation. Multivariable hierarchical logistic regression was used to determine the adjusted association between campaign participation and post-PCI bleeding events. Prespecified subgroups were examined. Campaign hospitals were more often higher volume teaching facilities located in urban or suburban locations. After adjustment, campaign participation was associated with a significant reduction in the rate of bleeding (bleeding: adjusted odds ratio, 0.61 [95% CI, 0.53-0.71]). Campaign hospitals had a greater decrease in bleeding events than noncampaign hospitals. In a subgroup analysis, the reduction in bleeding was noted in non-ST-segment-elevation acute coronary syndrome and ST-segment-elevation myocardial infarction patients, but no significant reduction was seen in patients without acute coronary syndrome. Participation in the American College of Cardiology Reduce the Risk: PCI Bleed Campaign was associated with a significant reduction in post-PCI bleeding. Our results underscore that national quality improvement efforts can be associated with a significant impact on PCI outcomes.

Sections du résumé

BACKGROUND UNASSIGNED
The American College of Cardiology Reduce the Risk: PCI Bleed Campaign was a hospital-based quality improvement campaign designed to reduce post-percutaneous coronary intervention (PCI) bleeding events. The aim of the campaign was to provide actionable evidence-based tools for participants to review, adapt, and adopt, depending upon hospital resources and engagement.
METHODS UNASSIGNED
We used data from 8 757 737 procedures in the National Cardiovascular Data Registry between 2015 and 2021 to compare patient and hospital characteristics and bleeding outcomes among campaign participants (n=195 hospitals) and noncampaign participants (n=1384). Post-PCI bleeding risk was compared before and after campaign participation. Multivariable hierarchical logistic regression was used to determine the adjusted association between campaign participation and post-PCI bleeding events. Prespecified subgroups were examined.
RESULTS UNASSIGNED
Campaign hospitals were more often higher volume teaching facilities located in urban or suburban locations. After adjustment, campaign participation was associated with a significant reduction in the rate of bleeding (bleeding: adjusted odds ratio, 0.61 [95% CI, 0.53-0.71]). Campaign hospitals had a greater decrease in bleeding events than noncampaign hospitals. In a subgroup analysis, the reduction in bleeding was noted in non-ST-segment-elevation acute coronary syndrome and ST-segment-elevation myocardial infarction patients, but no significant reduction was seen in patients without acute coronary syndrome.
CONCLUSIONS UNASSIGNED
Participation in the American College of Cardiology Reduce the Risk: PCI Bleed Campaign was associated with a significant reduction in post-PCI bleeding. Our results underscore that national quality improvement efforts can be associated with a significant impact on PCI outcomes.

Identifiants

pubmed: 38410946
doi: 10.1161/CIRCINTERVENTIONS.123.013003
pmc: PMC10942247
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e013003

Déclaration de conflit d'intérêts

Dr Amin has institutional grant support (modest) from GE Healthcare and Chiesi. Dr Abbott has the following relationships with industry: research: Boston Scientific and Microport; consulting: Abbott, Medtronic, Penumbra, Shockwave, and Philips. Dr Masoudi had a contract with the American College of Cardiology for his role as the Chief Scientific Advisor, National Cardiovascular Data Registry. The other authors report no conflicts.

Auteurs

Andrea L Price (AL)

Indiana University Health, Indianapolis (A.L.P.).

Amit P Amin (AP)

Rush University Medical Center, Chicago, IL (A.P.A.).

Susan Rogers (S)

American College of Cardiology, Washington DC (S.R.).

John C Messenger (JC)

University of Colorado School of Medicine, Aurora (J.C.M.).

Issam D Moussa (ID)

Carle Heart & Vascular Institute, Carle Illinois College of Medicine, Urbana (I.D.M.).

Julie M Miller (JM)

Johns Hopkins University, Baltimore, MD (J.M.M.).

Jonathan Jennings (J)

HCA Healthcare, Nashville, TN (J.J.).

Frederick A Masoudi (FA)

Ascension Health, St. Louis, MO (F.A.M.).

J Dawn Abbott (JD)

Warren Alpert Medical School of Brown University, Brown University, Lifespan Cardiovascular Institute, Providence, RI (J.D.A.).

Rebecca Young (R)

Duke Clinical Research Institute, Durham, NC (R.Y., D.M.W.).

Daniel M Wojdyla (DM)

Duke Clinical Research Institute, Durham, NC (R.Y., D.M.W.).

Sunil V Rao (SV)

NYU Langone Health System (S.V.R.).

Classifications MeSH