A database on the abundance of environmental antibiotic resistance genes.

Anti-Bacterial Agents / pharmacology China Drug Resistance, Microbial / genetics Genes, Bacterial Microbiota Databases, Genetic

Journal

Scientific data
ISSN: 2052-4463
Titre abrégé: Sci Data
Pays: England
ID NLM: 101640192

Informations de publication

Date de publication:
27 Feb 2024
Historique:
received: 05 10 2023
accepted: 20 02 2024
medline: 29 2 2024
pubmed: 28 2 2024
entrez: 27 2 2024
Statut: epublish

Résumé

Antimicrobial resistance (AMR) poses a severe threat to global health. The wide distribution of environmental antibiotic resistance genes (ARGs), which can be transferred between microbiota, especially clinical pathogens and human commensals, contributed significantly to AMR. However, few databases on the spatiotemporal distribution, abundance, and health risk of ARGs from multiple environments have been developed, especially on the absolute level. In this study, we compiled the ARG occurrence data generated by a high-throughput quantitative PCR platform from 1,403 samples in 653 sampling sites across 18 provinces in China. The database possessed 291,870 records from five types of habitats on the abundance of 290 ARGs, as well as 8,057 records on the abundance of 30 mobile genetic elements (MGEs) from 2013 to 2020. These ARGs conferred resistance to major common types of antibiotics (a total of 15 types) and represented five major resistance mechanisms, as well as four risk ranks. The database can provide information for studies on the dynamics of ARGs and is useful for the health risk assessment of AMR.

Identifiants

DOI: 10.1038/s41597-024-03084-8 PMID: 38413616 PMC: PMC10899624
pubmed: 38413616
doi: 10.1038/s41597-024-03084-8
pii: 10.1038/s41597-024-03084-8
pmc: PMC10899624
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Dataset Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

250

Subventions

Organisme : National Natural Science Foundation of China (National Science Foundation of China)
ID : 32161143016
Organisme : National Natural Science Foundation of China (National Science Foundation of China)
ID : 42177362
Organisme : National Natural Science Foundation of China (National Science Foundation of China)
ID : 42250410328
Organisme : Belarusian Republican Foundation for Fundamental Research (BRFFR)
ID : GPNI GR no. 20212317

Informations de copyright

© 2024. The Author(s).

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Auteurs

Wenjuan Xu (W)

Xiamen Key Laboratory of Indoor Air and Health, Key Lab of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, 361021, China.
College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100049, China.

Zhizhen Pan (Z)

Xiamen Key Laboratory of Indoor Air and Health, Key Lab of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, 361021, China.

Yangyu Wu (Y)

Xiamen Key Laboratory of Indoor Air and Health, Key Lab of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, 361021, China.

Xin-Li An (XL)

Xiamen Key Laboratory of Indoor Air and Health, Key Lab of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, 361021, China.

Weiyi Wang (W)

College of Life Sciences, Institute of Life Sciences and Green Development, Hebei University, Baoding, 071002, China.

Boris Adamovich (B)

Research Laboratory of Aquatic Ecology, Belarusian State University, Minsk, 220030, Belarus.

Yong-Guan Zhu (YG)

Xiamen Key Laboratory of Indoor Air and Health, Key Lab of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, 361021, China.

Jian-Qiang Su (JQ)

Xiamen Key Laboratory of Indoor Air and Health, Key Lab of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, 361021, China. jqsu@iue.ac.cn.
ORCID: 0000-0003-1875-249X

Qiansheng Huang (Q)

Xiamen Key Laboratory of Indoor Air and Health, Key Lab of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, 361021, China. qshuang@iue.ac.cn.
National Basic Science Data Center, Beijing, 100190, China. qshuang@iue.ac.cn.
ORCID: 0000-0002-3788-3164

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › A database on the abundance of environmental...
questionsmedicales.fr › Régions géographiques › Asie › Extrême-Orient › Chine › A database on the abundance of environmental...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Résistance aux substances › Résistance microbienne aux médicaments › A database on the abundance of environmental...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Génome microbien › Génome bactérien › Gènes bactériens › A database on the abundance of environmental...
questionsmedicales.fr › Environnement et santé publique › Environnement › Écosystème › Biodiversité › Biote › Microbiote › A database on the abundance of environmental...
questionsmedicales.fr › Sciences de l'information › Mémorisation et recherche des informations › Bases de données comme sujet › Bases de données factuelles › Bases de données génétiques › A database on the abundance of environmental...