Iron-related Biomarkers in the Diagnosis and Management of Iron Disorders.
Iron
biomarkers
hepcidin
iron deficiency
iron-related disorders
serum ferritin.
Journal
Current medicinal chemistry
ISSN: 1875-533X
Titre abrégé: Curr Med Chem
Pays: United Arab Emirates
ID NLM: 9440157
Informations de publication
Date de publication:
19 Feb 2024
19 Feb 2024
Historique:
received:
01
06
2023
revised:
26
11
2023
accepted:
14
12
2023
medline:
28
2
2024
pubmed:
28
2
2024
entrez:
28
2
2024
Statut:
aheadofprint
Résumé
Iron deficiency and iron-related disorders are common health issues worldwide, affecting a significant proportion of the population. Diagnosis and management of these disorders rely heavily on using various iron-related biomarkers that can provide valuable clinical information. This review article provides an overview of the most commonly used iron-related biomarkers, including serum ferritin, transferrin saturation, soluble transferrin receptor, zinc protoporphyrin, and free erythrocyte protoporphyrin. Other emerging biomarkers, such as hepcidin and retinol-binding protein 4, are also discussed. Iron plays a vital role in various physiological processes, including oxygen transport, energy metabolism, and DNA synthesis. The article highlights the advantages and limitations of iron biomarkers and their clinical applications in diagnosing and managing iron deficiency and iron-related anemia. Using iron-related biomarkers in screening and monitoring programs can improve patient outcomes and reduce healthcare costs.
Sections du résumé
BACKGROUND
BACKGROUND
Iron deficiency and iron-related disorders are common health issues worldwide, affecting a significant proportion of the population. Diagnosis and management of these disorders rely heavily on using various iron-related biomarkers that can provide valuable clinical information.
OBJECTIVE
OBJECTIVE
This review article provides an overview of the most commonly used iron-related biomarkers, including serum ferritin, transferrin saturation, soluble transferrin receptor, zinc protoporphyrin, and free erythrocyte protoporphyrin. Other emerging biomarkers, such as hepcidin and retinol-binding protein 4, are also discussed.
RESULTS
RESULTS
Iron plays a vital role in various physiological processes, including oxygen transport, energy metabolism, and DNA synthesis. The article highlights the advantages and limitations of iron biomarkers and their clinical applications in diagnosing and managing iron deficiency and iron-related anemia.
CONCLUSION
CONCLUSIONS
Using iron-related biomarkers in screening and monitoring programs can improve patient outcomes and reduce healthcare costs.
Identifiants
pubmed: 38415440
pii: CMC-EPUB-138611
doi: 10.2174/0109298673263003231228060800
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
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