Evaluation of "appropriate use criteria" for surgical decision-making in lumbar degenerative spondylolisthesis. A controlled, multicentre, prospective observational study.

Appropriate use criteria Degenerative spondylolisthesis Outcome

Journal

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
ISSN: 1432-0932
Titre abrégé: Eur Spine J
Pays: Germany
ID NLM: 9301980

Informations de publication

Date de publication:
28 Feb 2024
Historique:
received: 15 10 2023
accepted: 03 01 2024
revised: 22 12 2023
medline: 28 2 2024
pubmed: 28 2 2024
entrez: 28 2 2024
Statut: aheadofprint

Résumé

Selecting patients with lumbar degenerative spondylolisthesis (LDS) for surgery is difficult. Appropriate use criteria (AUC) have been developed to clarify the indications for LDS surgery but have not been evaluated in controlled studies. This prospective, controlled, multicentre study involved 908 patients (561 surgical and 347 non-surgical controls; 69.5 ± 9.7y; 69% female), treated as per normal clinical practice. Their appropriateness for surgery was afterwards determined using the AUC. They completed the Core Outcome Measures Index (COMI) at baseline and 12 months' follow-up. Multiple regression adjusting for confounders evaluated the influence of appropriateness designation and treatment received on the 12-month COMI and achievement of MCIC (≥ 2.2-point-reduction). As per convention, appropriate (A) and uncertain (U) groups were combined for comparison with the inappropriate (I) group. For the adjusted 12-month COMI, the benefit of surgery relative to non-surgical care was not significantly greater for the A/U than the I group (p = 0.189). There was, however, a greater treatment effect of surgery for those with higher baseline COMI (p = 0.035). The groups' adjusted probabilities of achieving MCIC were: 83% (A/U, receiving surgery), 71% (I, receiving surgery), 50% (A/U, receiving non-surgical care), and 32% (I, receiving non-surgical care). A/U patients receiving surgery had the highest chances of achieving MCIC, but the AUC were not able to identify which patients had a greater treatment effect of surgery relative to non-surgical care. The identification of other characteristics that predict a greater treatment effect of surgery, in addition to baseline COMI, is required to improve decision-making.

Identifiants

pubmed: 38416192
doi: 10.1007/s00586-024-08157-1
pii: 10.1007/s00586-024-08157-1
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

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Auteurs

Anne F Mannion (AF)

Spine Centre Division, Department of Teaching, Research and Development, Schulthess Klinik, Lengghalde 2, 8008, Zurich, Switzerland. anne.mannion@yahoo.com.

Francine Mariaux (F)

Spine Centre Division, Department of Teaching, Research and Development, Schulthess Klinik, Lengghalde 2, 8008, Zurich, Switzerland.

Paul M Werth (PM)

Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.

Adam M Pearson (AM)

Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.

Jon D Lurie (JD)

Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.

Tamas F Fekete (TF)

Spine Centre, Schulthess Klinik, Zurich, Switzerland.

Markus Kohler (M)

Bethesda Spital Basel, Basel, Switzerland.

Daniel Haschtmann (D)

Spine Centre, Schulthess Klinik, Zurich, Switzerland.

Frank S Kleinstueck (FS)

Spine Centre, Schulthess Klinik, Zurich, Switzerland.

Dezsoe Jeszenszky (D)

Spine Centre, Schulthess Klinik, Zurich, Switzerland.

Markus Loibl (M)

Spine Centre, Schulthess Klinik, Zurich, Switzerland.

Philippe Otten (P)

Clinique Générale, Fribourg, Switzerland.

Michael Norberg (M)

Centre Médical de Lavey-les-Bains, Lavey-les-Bains, Switzerland.

François Porchet (F)

Spine Centre, Schulthess Klinik, Zurich, Switzerland.

Classifications MeSH