Evaluation of cannabimimetic effects of selected minor cannabinoids and Terpenoids in mice.

Cannabidiol Cannabinol Drug discrimination THCV Tetrahydrocannabinol β-Caryophyllene

Journal

Progress in neuro-psychopharmacology & biological psychiatry
ISSN: 1878-4216
Titre abrégé: Prog Neuropsychopharmacol Biol Psychiatry
Pays: England
ID NLM: 8211617

Informations de publication

Date de publication:
26 Feb 2024
Historique:
received: 07 12 2023
revised: 23 02 2024
accepted: 24 02 2024
medline: 29 2 2024
pubmed: 29 2 2024
entrez: 28 2 2024
Statut: aheadofprint

Résumé

The cannabis plant contains several cannabinoids, and many terpenoids that give cannabis its distinctive flavoring and aroma. Δ Δ All minor cannabinoids showed measurable cannabinoid 1 (CB In summary, only some of myriad cannabinoids and other chemicals found in the cannabis plant bind potently to the identified cannabinoid receptors. Further, only four of the compounds tested herein [Δ

Sections du résumé

BACKGROUND BACKGROUND
The cannabis plant contains several cannabinoids, and many terpenoids that give cannabis its distinctive flavoring and aroma. Δ
METHODS METHODS
Δ
RESULTS RESULTS
All minor cannabinoids showed measurable cannabinoid 1 (CB
CONCLUSION CONCLUSIONS
In summary, only some of myriad cannabinoids and other chemicals found in the cannabis plant bind potently to the identified cannabinoid receptors. Further, only four of the compounds tested herein [Δ

Identifiants

pubmed: 38417478
pii: S0278-5846(24)00052-6
doi: 10.1016/j.pnpbp.2024.110984
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

110984

Informations de copyright

Copyright © 2024. Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Jenny L Wiley (JL)

RTI International, Research Triangle Park, NC, USA.

Julie A Marusich (JA)

RTI International, Research Triangle Park, NC, USA. Electronic address: jmarusich@rti.org.

Bruce E Blough (BE)

RTI International, Research Triangle Park, NC, USA.

Ojas Namjoshi (O)

RTI International, Research Triangle Park, NC, USA.

Marcus Brackeen (M)

RTI International, Research Triangle Park, NC, USA.

Luli R Akinfiresoye (LR)

United States Department of Justice, Drug Enforcement Administration, Diversion Control Division, Drug and Chemical Evaluation Section, 8701 Morrissette Drive, Springfield, VA, USA.

Teneille D Walker (TD)

United States Department of Justice, Drug Enforcement Administration, Diversion Control Division, Drug and Chemical Evaluation Section, 8701 Morrissette Drive, Springfield, VA, USA.

Cassandra Prioleau (C)

United States Department of Justice, Drug Enforcement Administration, Diversion Control Division, Drug and Chemical Evaluation Section, 8701 Morrissette Drive, Springfield, VA, USA.

Daniel G Barrus (DG)

RTI International, Research Triangle Park, NC, USA.

Thomas F Gamage (TF)

RTI International, Research Triangle Park, NC, USA; Department of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA.

Classifications MeSH